Publications Found (6327)
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Synthetic biology lies on the interface between natural and artificial life. It consists of assembly biological components into artificially configured systems. A main foc...

(2019) | The 2018 Conference on Artificial Life: A Hybrid of the European Conference on Artificial Life (ECAL) and the International Conference on the Synthesis and Simulation of Living Systems (ALIFE)
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alan shen, Leon Deouell, hansjochen heinze, hermann hinrichs, julia w y kam, leon y deouell, robert t knight, sandon griffin, shawn patel

Abstract Recent advances in dry electrodes technology have facilitated the recording of EEG situations not previously possible, thanks to relatively swift electrode preparation and avoidance applying gel subject's hair. However, become a true alternative, these systems should be compared state-of-the-art wet commonly used clinical or research applications. In our study, we conducted systematic comparison application speed, subject comfort,...

(2019) | NeuroImage
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carlos aleman, david zanuy, deborah e shalev, omer agazani, Meital Reches, Sivan Nir, Tal Zada

The accumulation of bacteria on surfaces is currently one the greatest concerns for management proper healthcare systems, water and energy. Here, we describe mechanism by which a single peptide forms two pH-dependent supramolecular particles that resist bacterial contamination. By using NMR molecular dynamics (MD), determined structures monomers showed forces directing self-assembly each structure under different conditions. These assemblies...

(2019) | Nanoscale
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guy cinamon, Ofer Mandelboim, paola kucan brlic, pini tsukerman, stipan jonjic, tihana lenac rovis

Poliovirus receptor (PVR, CD155) has recently been gaining scientific interest as a therapeutic target in the field of tumor immunology due to its prominent endogenous and immune functions. In contrast healthy tissues, PVR is expressed at high levels several human malignancies seems have protumorigenic therapeutically attractive properties that are currently being investigated recombinant oncolytic virotherapy. More intriguingly, participates...

(2019) | Cellular & Molecular Immunology
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bradley t hyman, caitlin commins, george a carlson, julia schiantarelli, marc aurel busche, naomi klickstein, Israel Nelken, simon dujardin, susanne wegmann, tarun v kamath

The coexistence of amyloid-? (A?) plaques and tau neurofibrillary tangles in the neocortex is linked to neural system failure cognitive decline Alzheimer?s disease. However, underlying neuronal mechanisms are unknown. By employing vivo two-photon Ca2+ imaging layer 2/3 cortical neurons mice expressing human A? tau, we reveal a dramatic tau-dependent suppression activity silencing many neurons, which dominates over A?-dependent hyperactivity....

(2019) | Nature Neuroscience
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anat iosubamir, fang bai, Assaf FRIEDLER, guy mayer, henribaptiste marjault, jose n onuchic, luhua song, ola karmi, patricia a jennings, rachel nechushtai, ron mittler, Sagi Tamir, yangsung sohn

Suppression of apoptosis is a key Hallmark cancer cells, and reactivation major avenue for therapy. We reveal an interaction between the two anti-apoptotic proteins iASPP NAF-1, which are overexpressed in many types cells tumors. inhibitory member ASPP protein family, whereas NAF-1 belongs to NEET 2Fe?2S family. show that stimulated interact during apoptosis. Using peptide array screening computational methods we mapped interfaces both...

(2019) | Chemical Science
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andreas kleiner, benny moldovanu, Alex Gershkov, xianwen shi

We model a situation where ex ante opinions in legislature are dichotomous but cross traditional left-right party lines, e.g., crucial decisions on ethical issues such as gay marriage and abortion, or joining/exiting an economic/political union. In addition to the two "extreme" positions left right, we consider effect of compromise alternative whose location may be endogenous. compare sequential, binary voting schemes conducted by privately...

(2019) |
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Ami Citri, Gal Atlan
(2019) | TheScienceBreaker
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Noam Nisan, shahar dobzinski, yakov babichenko
(2019) | Proceedings of the 51st Annual ACM SIGACT Symposium on Theory of Computing - STOC 2019
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We introduce a `concrete complexity' model for studying algorithms matching in bipartite graphs. The is based on the "demand query" used combinatorial auctions. Most (but not all) known seem to be translatable into this including exact, approximate, sequential, parallel, and online ones. A perfect graph can found with O(n^{3/2}) demand queries (in n vertices each side) our main open problem either improve upper bound or prove lower bound. An...

(2019) | arXiv preprint arXiv:1906.04213
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chaim i garfinkel, edwin p gerber, Chaim Garfinkel, ian p white, luke d oman, m jucker, valentina aquila

AbstractTropospheric features preceding sudden stratospheric warming events (SSWs) are identified using a large compendium of obtained from chemistry?climate model. In agreement with recen...

(2019) | Journal of Climate
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nadav steinberg, Zvi Wiener, yevgeny mugerman

We study a regulation that increased mutual funds' risk salience through name change. Using daily fund flow data and several identification strategies, we find requiring certain funds to affix an exclamation mark ("!") their names caused statistically economically significant decline in net flows, with larger effect on inflows than outflows. The mark?s impact stems from retail investors, both those seek financial advice invest independently....

(2019) |
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Omri Abend, dan eldad, Daniel Hershcovich, Elior Sulem, Leshem Choshen

The non-indexed parts of the Internet (the Darknet) have become a haven for both legal and illegal anonymous activity. Given magnitude these networks, scalably monitoring their activity necessarily relies on automated tools, notably NLP tools. However, little is known about what characteristics texts communicated through Darknet have, how well off-the-shelf tools do this domain. This paper tackles gap performs an in-depth investigation text...

(2019) | arXiv preprint arXiv:1905.05543
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adi szeskin, alexandre hostettler, an tang, andrea schenk, anjany sekuboyina, avi bencohen, bjoern h menze, bram van ginneken, chiwing fu, chris pal, christian hulsemeyer, chunming li, colin jacobs, eli konen, eugene vorontsov, eyal klang, fabian lohofer, felix grun, felix hofmann, florian ettlinger, gabriel chartrand, gabriel efrain humpire mamani, georgios kaissis, grzegorz chlebus, hans meine, hao chen, hayit greenspan, Jacob Sosna, jan hendrik moltz, jana lipkova, jin qi, johan moreau, john lowengrub, Leo Joskowicz, julian walter holch, jurgen hesser, karsten roth, luc soler, marcel beetz, marie piraud, markus rempfler, miao le, michal drozdzal, michal marianne amitai, naama levcohain, patrick bilic, patrick ferdinand christ, phengann heng, ping zhou, qi dou, Refael Vivanti, rickmer braren, samuel kadoury, tomasz k konopczynski, volker heinemann, wieland h sommer, xiao han, xiaojuan qi, xiaomeng li

In this work, we report the set-up and results of Liver Tumor Segmentation Benchmark (LITS) organized in conjunction with IEEE International Symposium on Biomedical Imaging (ISBI) 2016 Conference On Medical Image Computing Computer Assisted Intervention (MICCAI) 2017. Twenty four valid state-of-the-art liver tumor segmentation algorithms were applied to a set 131 computed tomography (CT) volumes different types contrast levels...

(2019) | arXiv preprint arXiv:1901.04056
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Reuven Amitai, gila kahila bargal, Gila Kahila Bar-Gal

It should not come as a surprise that the Mamluks took their horses very seriously. The mainstay of military might was large mobile field army mostly made up mounted archers. In this they were similar to armies Eurasian Steppe. However, unlike Mongols and Turkmens, Mamluk primarily fed by grazing, but rather fodder. Like soldiers themselves, mounts ?city dwellers,? although may have also spent some time during every year out in country. This,...

(2019) |
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a sonnino, Elliot Berry, d mattioni, Denis Lairon, Elliot M Berry, g brunori, l m donini, lluis serramajem, m stefanova, massimo iannetta, roberto capone, sandro dernini, suzanne piscopo
(2019) |
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aravind kumar jayasankar, mason n dean, ronald seidel, Ron Shahar

When describing the architecture and ultrastructure of animal skeletons, introductory biology, anatomy histology textbooks typically focus on few bone cartilage types prevalent in humans. In reality, are far more diverse kingdom, particularly within fishes, where exist that characterized by features anomalous or even pathological human skeletons. Here, we discuss curious complex architectures fish shark ray cartilage, highlighting...

(2019) |
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