Publications Found (7115)
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ashley shin, katharine lunny, robert continetti, strasser, Daniel Strasser, yanice benitez, yishai albeck
(2019) | Angewandte Chemie
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Guy Bloch, eli eisenberg, erez levanon, esther hazan, hagai shpigler, hagit porath, mark robert band, Mira Cohen, yehuda benshahar

Colonies of the bumblebee Bombus terrestris are characterized by wide phenotypic variability among genetically similar full-sister workers, suggesting a major role for epigenetic processes. Here, we report high level ADAR-mediated RNA editing in bumblebee, despite lack an ADAR1-homolog. We identify 1.15 million unique genomic sites, and 164 recoding sites residing 100 protein coding genes, including ion channels, transporters, receptors...

(2019) | Nature Communications
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antoine clery, erez levanon, frederic allain, georgina barnabas, gil levkowitz, Jakob Biran, Rotem Karni, maxim mogilevsky, miri danangotthold, odelia shimshon, polina denichenko, saran kumar, Tamar Geiger, thomas welte, Eylon Yavin

Alternative splicing, a fundamental step in gene expression, is deregulated many diseases. Splicing factors (SFs), which regulate this process, are up- or down regulated mutated several diseases including cancer. To date, there no inhibitors that directly inhibit the activity of SFs. We designed decoy oligonucleotides, composed repeats RNA motif, recognized by single SF. Here we show oligonucleotides targeting splicing RBFOX1/2, SRSF1 and...

(2019) | Nature Communications
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geula hanin, jochen klein, sebastian lobentanzer, Hermona Soreq

Recent reports revealed massive overlaps between the molecular pathologies of schizophrenia (SCZ) and bipolar disorder (BD), but did not address prominent clinical differences men women patients with these syndromes corresponding neurotransmitter transcript regulators their biological features. Here, we report sex-specific divergence central cholinergic networks in large patient brain datasets. Connectome analyses based on single cell- small...

(2019) | bioRxiv
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Alexander Lubotzky, Alex Lubotzky, Ori Parzanchevski

Ramanujan graphs are whose spectrum is bounded optimally. Such have found numerous applications in combinatorics and computer science. In recent years, a high dimensional theory has emerged. this paper these developments surveyed. After explaining their connection to the conjecture we will present some old new results with an emphasis on random walks discrete objects Euclidean spheres. The latter lead "golden gates" which of importance...

(2019) | arXiv preprint arXiv:1904.03533
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emanuele petruzzella, Dan Gibson, hana kostrhunova, jana kasparkova, viktor brabec
(2019) | Chemistry: A European Journal
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galya mondererrothkoff, laura malkifeldman, malka nissimrafinia, marina risman, matthias groszer, Eran Meshorer, nitzan tal, odem shani, Sagiv Shifman, vera medvedeva

Mutations in AUTS2 are associated with autism, intellectual disability, and microcephaly. is expressed the brain interacts polycomb proteins, yet it still unclear how mutations lead to neurodevelopmental phenotypes. Here we report that when neuronal differentiation initiated, there a shift expression from long isoform short isoform. Yeast two-hybrid screen identified splicing factor SF3B1 as an interactor of both isoforms, whereas group PCGF3...

(2019) | Molecular Psychiatry
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gabriel leitner, lavon, roth, wolfenson, David Wolfenson
(2019) | Bioscientifica Proceedings
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abigail fisher, alexandra burt, aline jelenkovic, amie hwang, antti latvala, ariel knafonoam, brooke huibregtse, carol franz, catarina almqvist, catharina van beijsterveldt, catherine derom, catherine tuvblad, clare llewellyn, david butler, David Mankuta, dorret boomsma, duarte freitas, elliot tuckerdrob, emanuela medda, esther rebato, fazil aliev, feng ning, fuling, gonneke willemsen, hermine maes, hoeuk jeong, jaakko kaprio, jennifer harris, jina kim, john hopper, joohon sung, jooyeon lee, jose maia, judy silberg, karri silventoinen, keith whitfield, kelly klump, kimberly saudino, Ariel Knafo-Noam, laura baker, lior abramson, lorenza nistico, maarit piirtola, mami tanaka, margaret gatz, masumi sugawara, matt mcgue, meike bartels, michael lyons, paige harden, patrik magnusson, paul lichtenstein, reijo sund, robert krueger, robert vlietinck, robin corley, ruth loos, sari aaltonen, satoko matsumoto, sevgi oncel, shandell pahlen, sooji lee, tessa cutler, thomas mack, thomas sevenius nilsen, thorkild sorensen, tracy nelson, vilhelmina ullemar, virgilia toccaceli, wendy cozen, william kremen, yoonmi hur, yoshie yokoyama, zengchang pang
(2019) | Obesity
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Daniel Rosenfeld, yannian zhu, youtong zheng, zhanqing
(2019) | Geophysical Research Letters
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Zach Adam, alon savidor, alona kerenpaz, elinor avivsharon, junping chen, Leah Naveh, mor rozenberg
(2019) | Frontiers in Plant Science
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adva livny, alik palatnik, baruch schwarz, naomi prusak, osama swidan, Baruch (Education) Schwarz

Integrating collaborative settings in mathematics classrooms is challenging. The main challenge concerns adaptive guidance?guidance that takes into account the needs of learners. This guidance depends on teacher?s understanding progression group work. Understanding this when teacher organizes several groups a classroom towards conceptual has been impracticable so far. In paper, we present an environment, System for Advancing Group Learning...

(2019) | Unterrichtswissenschaft
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Micha Asscher, elishama sorek, rabin rajan methikkalam, roey sagi, sujith ramakrishnan

Low-energy electrons are known to play a fundamental role in activating small molecules interstellar chemistry. Here we illustrate the electron-induced activation of inert molecule methane while sandwiched between two 50 monolayers thick layers amorphous solid water (ASW) on ruthenium substrate at 25 K by employing externally supplied low-energy (5 eV) under ultrahigh vacuum conditions. We demonstrate how electron transmission through ASW...

(2019) | Journal of Physical Chemistry C
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elisha svetitsky, Nadav Katz

The core concept of quantum simulation is the mapping an inaccessible system onto a controllable one by identifying analogous dynamics. We map Dirac equation relativistic mechanics in 3+1 dimensions multi-level superconducting Josephson circuit. Resonant drives determine particle mass and momentum state represents internal spinor dynamics, which are cast language optics. degeneracy spectrum corresponds to bright/dark states within spin...

(2019) | Physical Review A
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bertrand czarny, edward kaihua chow, Dan Gibson, giorgia pastorin, lissa ooi, maria babak, tan boon toh, wee han ang, yang zhi
(2019) | Angewandte Chemie
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