Researcher interests: Identifying the genetic elements that make species resistance to extreme environments, cancer and aging. Identifying novel disease genes.
FACULTY / SCHOOL: School of Medicine - IMRIC
DEPARTMENT: Developmental Biology and Cancer Research
Selected Publications
a high throughput screening and computation platform for identifying synthetic promoters with enhanced cell state specificity specs (2019)|
Nature Communications|
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myorg mutations a major cause of recessive primary familial brain calcification (2019)|
Current Neurology and Neuroscience Reports|
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evolutionary motifs a novel way to define gene evolution across a thousand species (2019)|
F1000Research|
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expanded cug repeats trigger disease phenotype and expression changes through the rnai machinery in c elegans (2019)|
Journal of Molecular Biology|
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mapping global and local coevolution across 600 species to identify novel homologous recombination repair genes (2019)|
Genome Research|
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myorg is associated with recessive primary familial brain calcification (2019)|
Annals of clinical and translational neurology|
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schlafen2 mutation in mice causes an osteopetrotic phenotype due to a decrease in the number of osteoclast progenitors (2018)|
Scientific Reports|
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mutated mitf e87r in melanoma enhances tumor progression via s100a4 (2018)|
Journal of Investigative Dermatology|
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shld2 fam35a co operates with rev7 to coordinate dna double strand break repair pathway choice (2018)|
The EMBO Journal|
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shld2 fam35a co operates with rev7 to coordinate dna double strand break repair pathway choice (2018)|
The EMBO Journal|
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synthetic rna based immunomodulatory gene circuits for cancer immunotherapy (2017)|
Cell|
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synthetic rna based immunomodulatory gene circuits for cancer immunotherapy (2017)|
PMC|
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identification of small rna pathway genes using patterns of phylogenetic conservation and divergence (2013)|
Nature|
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