Researcher interests: Translocation of proteins and nucleic acid across the nuclear envelope of animal and plant cells. Entry of viral genome into nuclei of infected cells, isolation and characterization of plant cells cytosolic receptors required for nuclei import, the use of specific synthetic peptides to block nuclear import of proteins and nucleic acids, as a way to inhibit viral infection.
FACULTY / SCHOOL: Faculty of Science
Selected Publications
hiv 1 integrase derived peptides and compositions comprising them (2018)|
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tylcv is movement in planta does not require v2 protein (2015)|
Virology|
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the disordered region of arabidopsis vip1 binds the agrobacterium vire2 protein outside its dna binding site (2014)|
Protein Engineering Design & Selection|
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a tandem in situ peptide cyclization through trifluoroacetic acid cleavage (2014)|
Angewandte Chemie|
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frontispiece a tandem in situ peptide cyclization through trifluoroacetic acid cleavage (2014)|
Angewandte Chemie|
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structure activity relationship studies using peptide arrays the example of hiv 1 rev integrase interaction (2013)|
MedChemComm|
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monitoring the hiv 1 integrase enzymatic activity using atomic force microscopy in a 2ltr system (2013)|
Chemical Communications|
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peptides that inhibit hiv 1 integrase by blocking its protein protein interactions (2012)|
FEBS Journal|
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a comparative study of backbone versus side chain peptide cyclization application for hiv 1 integrase inhibitors (2012)|
Bioorganic & Medicinal Chemistry|
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strategies to inhibit viral protein nuclear import hiv 1 as a target ()|
Biochimica et Biophysica Acta|
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