Researcher interests: Development of an original nano-delivery platform for improving the oral absorption of poorly absorbed drugs  Taher Nassar, Suha Attili-Qadry, Ayala Rohald; Natasha Nayarkin and Simon Benita Based on combined technologies the aim of this novel nanoplatform is to release and enhance the intestinal absorption of drugs by encapsulating them in nanocapsules that are embedded in microparticles. This nanoplatform was shown to bypass the liver where part of the drug dose is degraded prior to reaching the blood circulation following oral administration since the drug-loaded nanocapsules permeated through the intestinal mucosa and reached the blood circulation via the lymphatic system.
FACULTY / SCHOOL: School of Medicine - IMRIC

Selected Publications

amit badihi, Simon Benita, marina frusiczlotkin, sandrine benhamron, t tzur, taher nassar, Yoram Soroka
topical nano encapsulated cyclosporine formulation for atopic dermatitis treatment (2019)| Nanomedicine: Nanotechnology, Biology and Medicine| Read more
ayala rohald, Simon Benita, dinorah barasch, Moshe Kotler, natalya naraykin, orit amsalem, ponnandy prabhu, taher nassar
nanocapsules embedded in microparticles for enhanced oral bioavailability and efficacy of lopinavir as an anti aids drug (2019)| Journal of Drug Targeting| Read more
amit badihi, Simon Benita, leslie rebibo, taher nassar
drug delivery systems (2019)| | Read more
alessio f peritore, Simon Benita, Ehud Ziv, enrico gugliandolo, liat soudrykochavi, natalya naraykin, rosanna di paola, salvatore cuzzocrea, taher nassar
pharmacodynamical effects of orally administered exenatide nanoparticles embedded in gastro resistant microparticles (2018)| European Journal of Pharmaceutics and Biopharmaceutics| Read more
Simon Benita, dina ben yehuda, dina benyehuda, ihab abd elrahman, noha khairi, riki perlman, taher nassar
minit livin conjugated to targeted nanoparticles inhibits tumorigenicity (2018)| Blood| Read more
Simon Benita, frederic lallemand, j l bourges, jeansebastien garrigue, mathieu schmitt, robert gurny
cyclosporine a delivery to the eye a comprehensive review of academic and industrial efforts (2017)| European Journal of Pharmaceutics and Biopharmaceutics| Read more
Simon Benita, orit amsalem, philip lazarovici, sandrine benhamron, taher nassar, Eylon Yavin
solid nano in nanoparticles for potential delivery of sirna (2017)| Journal of Controlled Release| Read more
amit badihi, Simon Benita, claes d enk, mano robinpour, Nir Debotton
dermal absorption behavior of fluorescent molecules in nanoparticles on human and porcine skin models (2017)| International Journal of Pharmaceutics| Read more
aiman abu ammar, Simon Benita, Dan Gibson, raji raveendran, taher nassar
a lipophilic pt iv oxaliplatin derivative enhances antitumor activity (2016)| Journal of Medicinal Chemistry| Read more
Simon Benita, orit amsalem, taher nassar
withdrawn patent as per the latest uspto withdrawn list nano delivery systems for sirna (2016)| | Read more

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