Researcher interests: Development of an original nano-delivery platform for improving the oral absorption of poorly absorbed drugs Taher Nassar, Suha Attili-Qadry, Ayala Rohald; Natasha Nayarkin and Simon Benita Based on combined technologies the aim of this novel nanoplatform is to release and enhance the intestinal absorption of drugs by encapsulating them in nanocapsules that are embedded in microparticles. This nanoplatform was shown to bypass the liver where part of the drug dose is degraded prior to reaching the blood circulation following oral administration since the drug-loaded nanocapsules permeated through the intestinal mucosa and reached the blood circulation via the lymphatic system.
FACULTY / SCHOOL: School of Medicine - IMRIC
DEPARTMENT: School of Pharmacy- Institute for Drug Research
Selected Publications
topical nano encapsulated cyclosporine formulation for atopic dermatitis treatment (2019)|
Nanomedicine: Nanotechnology, Biology and Medicine|
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nanocapsules embedded in microparticles for enhanced oral bioavailability and efficacy of lopinavir as an anti aids drug (2019)|
Journal of Drug Targeting|
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drug delivery systems (2019)|
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pharmacodynamical effects of orally administered exenatide nanoparticles embedded in gastro resistant microparticles (2018)|
European Journal of Pharmaceutics and Biopharmaceutics|
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minit livin conjugated to targeted nanoparticles inhibits tumorigenicity (2018)|
Blood|
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cyclosporine a delivery to the eye a comprehensive review of academic and industrial efforts (2017)|
European Journal of Pharmaceutics and Biopharmaceutics|
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solid nano in nanoparticles for potential delivery of sirna (2017)|
Journal of Controlled Release|
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dermal absorption behavior of fluorescent molecules in nanoparticles on human and porcine skin models (2017)|
International Journal of Pharmaceutics|
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a lipophilic pt iv oxaliplatin derivative enhances antitumor activity (2016)|
Journal of Medicinal Chemistry|
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withdrawn patent as per the latest uspto withdrawn list nano delivery systems for sirna (2016)|
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