Researcher interests: Pharmacodynamic aspects of drug delivery systems. Optimized drug delivery according to the kinetics of drug action. The effect of disease states on the kinetics of drug action and on bone resorption. Lymphatic drug absorption. Pharmacokinetics and pharmacodynamics of peptides. Structure-bioavailability of peptides.
FACULTY / SCHOOL: School of Medicine - IMRIC
DEPARTMENT: School of Pharmacy- Institute for Drug Research
Selected Publications
a meta opinion cannabinoids delivered to oral mucosa by a spray for systemic absorption are rather ingested into gastro intestinal tract the influences of fed fasting states (2019)|
Expert Opinion on Drug Delivery|
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myristoylation confers oral bioavailability and improves the bioactivity of c myd 4 4 a cyclic peptide inhibitor of myd88 (2019)|
Molecular Pharmaceutics|
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development of a novel backbone cyclic peptide inhibitor of the innate immune tlr il1r signaling protein myd88 (2018)|
Scientific Reports|
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orally active peptides is there a magic bullet (2018)|
Angewandte Chemie|
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oral aktive peptide gibt es ein patentrezept (2018)|
Angewandte Chemie|
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pro nanoliposphers pnl for improved oral bioavailability of insoluble drugs (2018)|
American Journal of Pharmacology and Pharmacotherapeutics|
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enhancing oral bioavailability of cyclic rgd hexa peptides by the lipophilic prodrug charge masking approach redirection of peptide intestinal permeability from paracellular to transcellular pathway (2018)|
Molecular Pharmaceutics|
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the effect of piperine pro nano lipospheres on direct intestinal phase ii metabolism the raloxifene paradigm of enhanced oral bioavailability (2018)|
Molecular Pharmaceutics|
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investigation of intestinal absorption enhancers individual vs blends with the carbamoylphosphonate js403 (2018)|
Journal of Bioequivalence & Bioavailability|
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overcoming the lack of oral availability of cyclic hexapeptides design of a selective and orally available ligand for the integrin αvβ3 (2017)|
Angewandte Chemie|
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dp 155 a lecithin derivative of indomethacin is a novel nonsteroidal antiinflammatory drug for analgesia and alzheimer s disease therapy (2007)|
Cns Drug Reviews|
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a novel phospholipid derivative of indomethacin dp 155 mixture of 1 steroyl and 1 palmitoyl 2 4 1 p chlorobenzoyl 5 methoxy 2 methyl 3 indolyl acetamido butanoyl sn glycero 3 phosophatidyl choline shows superior safety and similar efficacy in reducin (2006)|
Journal of Pharmacology and Experimental Therapeutics|
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