Researcher interests: The laboratory of molecular modeling and drug design develops algorithms and computer techniques and employs them, as well as other computational methods, for research in structural biology, modeling, and drug design.
A central activity in the laborato
FACULTY / SCHOOL: School of Medicine - IMRIC
DEPARTMENT: School of Pharmacy- Institute for Drug Research
Selected Publications
discovering highly selective and diverse ppar delta agonists by ligand based machine learning and structural modeling (2019)|
Scientific Reports|
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prediction and experimental confirmation of novelperipheral cannabinoid 1 receptor antagonists (2019)|
Journal of Chemical Information and Modeling|
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new drug candidates for liposomal delivery identified by computer modeling of liposomes remote loading and leakage (2017)|
Journal of Controlled Release|
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discovering novel and diverse iron chelators in silico (2016)|
Journal of Chemical Information and Modeling|
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computational discovery and experimental confirmation of tlr9 receptor antagonist leads (2016)|
Journal of Chemical Information and Modeling|
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nano mupirocin enabling the parenteral activity of mupirocin (2016)|
European Journal of Nanomedicine|
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structural basis of glycogen branching enzyme deficiency and pharmacologic rescue by rational peptide design (2015)|
Human Molecular Genetics|
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iterative stochastic elimination for solving complex combinatorial problems in drug discovery (2014)|
Israel Journal of Chemistry|
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effect of solubilizing agents on mupirocin loading into and release from pegylated nanoliposomes (2014)|
Journal of Pharmaceutical Sciences|
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computer aided design of liposomal drugs in silico prediction and experimental validation of drug candidates for liposomal remote loading (2014)|
Journal of Controlled Release|
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Success Stories & related Product & PR
Pepticom Ltd.
Pepticom emerged out of Prof. Amiram Goldblum laboratory in the Hebrew University in Jerusalem. Pepticom’s proprietary technology enables the design and discovery of advanced peptide-based drug candidates quickly, comprehensively and...
