Researcher interests: liposomes , Relationship between physical and biological properties of biological membranes. Characterization of viral membranes. Relationship between lipid composition of cell membranes to membrane and cell functions. Involvement of lipids in the aging process. Application of liposomes in biomedical problems.
FACULTY / SCHOOL: School of Medicine - IMRIC

Selected Publications

Ahuva Cern, alexander tropsha, Yechezkel Barenholz, David Marcus, Amiram Goldblum
new drug candidates for liposomal delivery identified by computer modeling of liposomes remote loading and leakage (2017)| Journal of Controlled Release| Read more
andreas ingemann jensen, Yechezkel Barenholz, keren turjeman, kirill makedonski, noga yerushalmi, rivka cohen, sharon avkinnachum, tirtsa kleinman, Eylon Yavin
lipid assemblies and uses thereof and some ph and electrostatic modulating lipids to be used in said assemblies (2016)| | Read more
Ahuva Cern, allon moses, ayelet michaelgayego, Yechezkel Barenholz, erez koren, Amiram Goldblum, yaelle bavli, yan xiong
nano mupirocin enabling the parenteral activity of mupirocin (2016)| European Journal of Nanomedicine| Read more
Yechezkel Barenholz, dganit danino, hadas perlstein, peter gimeson, rivka cohen, Abraham Rubinstein, tanya turovsky
thermotropic behavior of celecoxib loaded beta casein micelles relevance to the improved bioavailability (2015)| European Journal of Nanomedicine| Read more
Ahuva Cern, Yechezkel Barenholz, einat nativroth, Amiram Goldblum
effect of solubilizing agents on mupirocin loading into and release from pegylated nanoliposomes (2014)| Journal of Pharmaceutical Sciences| Read more
Ahuva Cern, alexander tropsha, Yechezkel Barenholz, Amiram Goldblum
computer aided design of liposomal drugs in silico prediction and experimental validation of drug candidates for liposomal remote loading (2014)| Journal of Controlled Release| Read more
Yechezkel Barenholz, efrat sasson, haim ovadia, keren turjeman, nahum allon, pablo kizelsztein, Uri Raviv, tamar blumenfeld katzir, yaelle bavli, yaelle schilt
nano drugs based on nano sterically stabilized liposomes for the treatment of inflammatory neurodegenerative diseases ()| PLOS ONE| Read more
alexander andriyanov, Yechezkel Barenholz, Emma Portnoy, erez koren, Sara Eyal, nahum goldberg, semenenko inesa
therapeutic efficacy of combined pegylated liposomal doxorubicin and radiofrequency ablation comparing single and combined therapy in young and old mice ()| Journal of Controlled Release| Read more
Yechezkel Barenholz, haim ovadia, Ron Kohen, olga garbuzenko, pablo kizelsztein, rinat tabakman, veronica wasserman
the antioxidant tempamine in vitro antitumor and neuroprotective effects and optimization of liposomal encapsulation and release ()| Langmuir| Read more
alexander andriyanov, ariel steiner, Yechezkel Barenholz, Daniel Zucker, Uri Raviv
characterization of pegylated nanoliposomes co remotely loaded with topotecan and vincristine relating structure and pharmacokinetics to therapeutic efficacy ()| Journal of Controlled Release| Read more

Success Stories & related Product & PR

DOXIL (Caeylx)

DOXIL is indicated for the treatment of patients with ovarian cancer whose disease has progressed or recurred after platinum-based chemotherapy.

Product developed by:
Prof. Yechezkal Barenholz, Faculty of Medicine, Hebrew University & Prof....
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