Researcher interests: Gene regulation in spatial and temporal decisions in the early vertebrate embryo. Genes that regulate the dorso-ventral axis of the embryo. Regulation of the anterior-posterior axis of the embryo, interactions and regulation of Vitamin-A derived signals in the early embryo. Analysis of the teratogenic effects of Vitamin A. Cloning and characterization of novel developmental genes in higher vertebrates. Homeobox genes in the establishment of the early embryonic axes.
FACULTY / SCHOOL: School of Medicine - IMRIC
DEPARTMENT: Developmental Biology and Cancer Research
Selected Publications
chox cad characterization and rooster sperm preservation as a first step in the generation of transgenic chickens with modified homeobox genes (2019)|
|
Read more
retinoic acid signaling reduction recapitulates the effects of alcohol on embryo size (2019)|
Genesis|
Read more
insights into retinoic acid deficiency and the induction of craniofacial malformations and microcephaly in fetal alcohol spectrum disorder (2019)|
Genesis|
Read more
acetaldehyde inhibits retinoic acid biosynthesis to mediate alcohol teratogenicity (2018)|
Scientific Reports|
Read more
admp controls the size of spemann s organizer through a network of self regulating expansion restriction signals (2018)|
BMC Biology|
Read more
xenopus embryos to study fetal alcohol syndrome a model for environmental teratogenesis (2018)|
Biochemistry and Cell Biology|
Read more
special issue on fetal alcohol spectrum disorder1 (2018)|
Biochemistry and Cell Biology|
Read more
competition between ethanol clearance and retinoic acid biosynthesis in the induction of fetal alcohol syndrome1 (2018)|
Biochemistry and Cell Biology|
Read more
expression of the alk1 family of type i bmp admp receptors during gastrula stages in xenopus embryos (2017)|
The International Journal of Developmental Biology|
Read more
adhfe1 a novel enzyme involved in retinoic acid dependent hox activation (2017)|
The International Journal of Developmental Biology|
Read more
kinetic characterization and regulation of the human retinaldehyde dehydrogenase 2 enzyme during production of retinoic acid (2016)|
Biochemical Journal|
Read more
