Researcher interests: Cellular and molecular mechanisms in the formation of new blood vessels (angiogenesis) in health and disease. Developmental angiogenesis. Therapeutic angiogenesis in cardiovascular medicine. Anti-angiogenic cancer therapy. Oxygen regulated gene expression
FACULTY / SCHOOL: School of Medicine - IMRIC
DEPARTMENT: Developmental Biology and Cancer Research
Selected Publications
hippocampal neural stem cells facilitate access from circulation via apical cytoplasmic processes (2019)|
bioRxiv|
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intra tumoral metabolic zonation and resultant phenotypic diversification are dictated by blood vessel proximity (2019)|
Cell Metabolism|
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unique role for dentate gyrus microglia in neuroblast survival and in vegf induced activation (2019)|
Glia|
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vegf expands erythropoiesis via hypoxia independent induction of erythropoietin in noncanonical perivascular stromal cells (2019)|
Journal of Experimental Medicine|
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modulation of mknk2 alternative splicing by splice switching oligonucleotides as a novel approach for glioblastoma treatment (2018)|
Nucleic Acids Research|
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serine synthesis via phgdh is essential for heme production in endothelial cells (2018)|
Cell Metabolism|
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trained memory of human uterine nk cells enhances their function in subsequent pregnancies (2018)|
Immunity|
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hyperglycemia impairs neutrophil mobilization leading to enhanced metastatic seeding (2017)|
Cell Reports|
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composition for use in detection of sflt 14 (2017)|
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conditional islet hypovascularisation does not preclude beta cell expansion during pregnancy in mice (2017)|
Diabetologia|
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