Researcher interests: Investigation of genetic and molecular basis of cancer development; study of genes (coding and non-coding) to elucidate pathways for developing rational, effective therapeutic approaches to cancer. Study of WW domain-containing oxidoreductase (WWOX) tumor suppressor gene, inactivated in most common human cancers.
FACULTY / SCHOOL: School of Medicine - IMRIC
DEPARTMENT: Immunology and Cancer Research
Selected Publications
mir 16 1 3p and mir 16 2 3p possess strong tumor suppressive and anti metastatic properties in osteosarcoma (2019)|
International Journal of Cancer|
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wwox inhibits metastasis of triple negative breast cancer cells via modulation of mirnas (2019)|
Cancer Research|
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wwox somatic ablation in skeletal muscles alters glucose metabolism (2019)|
Molecular metabolism|
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fhit fdxr interaction in the mitochondria modulation of reactive oxygen species generation and apoptosis in cancer cells (2019)|
Cell Death and Disease|
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author correction wwox controls hepatic hif1α to suppress hepatocyte proliferation and neoplasia (2018)|
Cell Death and Disease|
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combined shrna over crispr cas9 as a methodology to detect off target effects and a potential compensatory mechanism (2018)|
Scientific Reports|
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tcl1a interacts with tp63 and enhances the survival of raji burkitt lymphoma cell line (2018)|
British Journal of Haematology|
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microenvironmental cues determine tumor cell susceptibility to neutrophil cytotoxicity (2018)|
Cancer Research|
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somatic loss of wwox is associated with tp53 perturbation in basal like breast cancer (2018)|
Cell Death and Disease|
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microrna 214 promotes hepatic stellate cell activation and liver fibrosis by suppressing sufu expression (2018)|
Cell Death and Disease|
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trpm2 mediates neutrophil killing of disseminated tumor cells (2018)|
Cancer Research|
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