Researcher interests: Human nuclear RNase P ribonucleoprotein in tRNA processing and transcription: (i) Assembly and reconstitution of the human catalytic ribonucleoprotein ribonuclease P.; (ii) Mechanism of action of human nuclear RNase P ribonucleoprotein in RNA polymerase III transcription; (iii) Role of human RNase P ribonucleoprotein in RNA polymerase I transcription.
FACULTY / SCHOOL: School of Medicine - IMRIC
DEPARTMENT: Microbiology and Molecular Genetics
Selected Publications
arginine dephosphorylation propels spore germination in bacteria (2019)|
Proceedings of the National Academy of Sciences of the United States of America|
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chance and necessity in the evolution of rnase p (2018)|
RNA|
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a role of human rnase p subunits rpp29 and rpp21 in homology directed repair of double strand breaks (2017)|
Scientific Reports|
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roles of rnase p and its subunits (2017)|
Trends in Genetics|
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targeted inhibition of wrn helicase replication stress and cancer (2017)|
Biochimica et Biophysica Acta|
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targeted inhibition of wrn helicase by external guide sequence and rnase p rna (2016)|
Biochimica et Biophysica Acta|
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human rnase p ribonucleoprotein is required for formation of initiation complexes of rna polymerase iii (2015)|
Nucleic Acids Research|
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rna binding properties of conserved protein subunits of human rnase p (2011)|
Nucleic Acids Research|
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archaeal eukaryal rnase p subunits functions and rna diversification (2010)|
Nucleic Acids Research|
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