Researcher interests: Design and application of chemical tools to image protease function in human pathology.
FACULTY / SCHOOL: School of Medicine - IMRIC
DEPARTMENT: School of Pharmacy- Institute for Drug Research
Selected Publications
mtorc1 activation in b cells confers impairment of marginal zone microarchitecture by exaggerating cathepsin activity (2018)|
Immunology|
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amphiphilic nanocarrier induced modulation of plk1 and mir 34a leads to improved therapeutic response in pancreatic cancer (2018)|
Nature Communications|
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ct imaging of enzymatic activity in cancer using covalent probes reveal a size dependent pattern (2018)|
Journal of the American Chemical Society|
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effect of cathepsin inhibition on metabolism and polarization of tumor associated macrophages (2018)|
Pancreatology|
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molecular imaging of cancer using x ray computed tomography with protease targeted iodinated activity based probes (2018)|
Nano Letters|
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image guided surgery using near infrared turn on fluorescent nanoprobes for precise detection of tumor margins (2018)|
Theranostics|
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cathepsin nanofiber substrates as potential agents for targeted drug delivery (2017)|
Journal of Controlled Release|
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new role for interleukin 13 receptor α1 in myocardial homeostasis and heart failure (2017)|
Journal of the American Heart Association|
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cysteine proteases in atherosclerosis (2017)|
FEBS Journal|
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comparative evaluation of polycyanoacrylates (2017)|
Acta Biomaterialia|
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