Researcher interests: Systems Biology of Transcription and Chromatin, Transcription regulation, Chromatin modifications, systematic yeast genetics.
FACULTY / SCHOOL: Faculty of Science
Selected Publications
deciphering eukaryotic gene regulatory logic with 100 million random promoters (2019)|
Nature Biotechnology|
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gene expression cartography (2019)|
Nature|
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fatalities in poisoned patients managed by medical toxicologists (2019)|
Clinical Toxicology|
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genetic screen of the yeast environmental stress response dynamics uncovers distinct regulatory phases (2019)|
Molecular Systems Biology|
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chip seq of plasma cell free nucleosomes identifies cell of origin gene expression programs (2019)|
bioRxiv|
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inferring geometric embeddings for single cell data (2019)|
Bulletin of the American Physical Society|
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dynamics of chromatin and transcription during transient depletion of the rsc chromatin remodeling complex (2019)|
Cell Reports|
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charting a tissue from single cell transcriptomes (2018)|
bioRxiv|
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temporal profiling of redox dependent heterogeneity in single cells (2018)|
eLife|
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author response temporal profiling of redox dependent heterogeneity in single cells (2018)|
|
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fine resolution mapping of tf binding and chromatin interactions (2018)|
Cell Reports|
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nuclear receptors control pro viral and antiviral metabolic responses to hepatitis c virus infection (2016)|
Nature Chemical Biology|
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perturb seq dissecting molecular circuits with scalable single cell rna profiling of pooled genetic screens (2016)|
Cell|
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perturb seq dissecting molecular circuits with scalable single cell rna profiling of pooled genetic screens (2016)|
PMC|
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high resolution sequencing and modeling identifies distinct dynamic rna regulatory strategies (2014)|
PMC|
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high resolution sequencing and modeling identifies distinct dynamic rna regulatory strategies (2014)|
Cell|
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a high throughput chromatin immunoprecipitation approach reveals principles of dynamic gene regulation in mammals (2012)|
Molecular Cell|
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a high throughput chromatin immunoprecipitation approach reveals principles of dynamic gene regulation in mammals (2012)|
Elsevier|
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metabolic labeling of rna uncovers principles of rna production and degradation dynamics in mammalian cells (2011)|
Nature Biotechnology|
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metabolic labeling of rna uncovers principles of rna production and degradation dynamics in mammalian cells (2011)|
PMC|
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