Researcher interests: Bioinorganic chemistry and medicinal chemistry. Targeting of anticancer agents. Interactions of small molecules and metal complexes with biopolymers. Toxicity of heavy metals. Inorganic coordination chemistry including synthesis, structural characterizati
FACULTY / SCHOOL: School of Medicine - IMRIC
DEPARTMENT: School of Pharmacy- Institute for Drug Research
Selected Publications
synthesis and cytotoxicity of water soluble dual and triple action satraplatin derivatives replacement of equatorial chlorides of satraplatin by acetates (2019)|
Inorganic Chemistry|
Read more
expanding the arsenal of ptiv anticancer agents multi action ptiv anticancer agents with bioactive ligands possessing a hydroxy functional group (2019)|
Angewandte Chemie|
Read more
dual targeting dual action platinum iv platform for enhanced anticancer activity and reduced nephrotoxicity (2019)|
Angewandte Chemie|
Read more
a subset of new platinum antitumor agents kills cells by a multimodal mechanism of action also involving changes in the organization of the microtubule cytoskeleton (2019)|
Journal of Medicinal Chemistry|
Read more
an anticancer pt iv prodrug that acts by mechanisms involving dna damage and different epigenetic effects (2019)|
Chemistry: A European Journal|
Read more
multi action pt iv anticancer agents do we understand how they work (2019)|
Journal of Inorganic Biochemistry|
Read more
triple action pt iv derivatives of cisplatin a new class of potent anticancer agents that overcome resistance (2018)|
Chemical Science|
Read more
epigenetic and antitumor effects of platinum iv octanoato conjugates (2017)|
Scientific Reports|
Read more
probing the interactions of cytotoxic pt 1s 2s dach 5 6 dimethyl 1 10 phenanthroline and its ptiv derivatives with human serum (2017)|
ChemMedChem|
Read more
synthesis characterization and in vitro and in vivo anticancer activity of pt iv derivatives of pt 1s 2s dach 5 6 dimethyl 1 10 phenanthroline (2017)|
Dalton Transactions|
Read more
a lipophilic pt iv oxaliplatin derivative enhances antitumor activity (2016)|
Journal of Medicinal Chemistry|
Read more