Researcher interests: Alternative splicing regulation in cancer. Splicing factors as a new type of oncogenes. Identification of splicing factor targets in vivo.
FACULTY / SCHOOL: School of Medicine - IMRIC
DEPARTMENT: Biochemistry and Molecular Biology
Selected Publications
specific inhibition of splicing factor activity by decoy rna oligonucleotides (2019)|
Nature Communications|
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2 apb and cbd mediated targeting of charged cytotoxic compounds into tumor cells suggests the involvement of trpv2 channels (2019)|
Frontiers in Pharmacology|
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long noncoding rna malat1 regulates cancer glucose metabolism by enhancing mtor mediated translation of tcf7l2 (2019)|
Cancer Research|
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intra tumoral metabolic zonation and resultant phenotypic diversification are dictated by blood vessel proximity (2019)|
Cell Metabolism|
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modulation of mknk2 alternative splicing by splice switching oligonucleotides as a novel approach for glioblastoma treatment (2018)|
Nucleic Acids Research|
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recapitulating the clinical scenario of brca associated pancreatic cancer in pre clinical models (2018)|
International Journal of Cancer|
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trpm2 mediates neutrophil killing of disseminated tumor cells (2018)|
Cancer Research|
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the role of alternative splicing in cancer drug resistance (2018)|
Current Opinion in Genetics & Development|
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ras ndash erk signaling induces phosphorylation of human tle1 and downregulates its repressor function (2017)|
Oncogene|
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activation dependent traf3 exon 8 alternative splicing is controlled by celf2 and hnrnp c binding to an upstream intronic element (2017)|
Molecular and Cellular Biology|
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long noncoding rna malat1 promotes hepatocellular carcinoma development by srsf1 upregulation and mtor activation (2017)|
Cancer Research|
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pfsr1 controls alternative splicing and steady state rna levels in plasmodium falciparum through preferential recognition of specific rna motifs (2015)|
Molecular Microbiology|
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