Researcher interests: Alternative splicing regulation in cancer. Splicing factors as a new type of oncogenes. Identification of splicing factor targets in vivo.
FACULTY / SCHOOL: School of Medicine - IMRIC

Selected Publications

antoine clery, erez levanon, frederic allain, georgina barnabas, gil levkowitz, Jakob Biran, Rotem Karni, maxim mogilevsky, miri danangotthold, odelia shimshon, polina denichenko, saran kumar, Tamar Geiger, thomas welte, Eylon Yavin
specific inhibition of splicing factor activity by decoy rna oligonucleotides (2019)| Nature Communications| Read more
amijai saragovi, Michael Berger, Ilan Stein, Rotem Karni, noam sternginossar, Eli Pikarsky, pushkar malakar, roni winkler
long noncoding rna malat1 regulates cancer glucose metabolism by enhancing mtor mediated translation of tcf7l2 (2019)| Cancer Research| Read more
adi mogilevsky, florian heyd, Rotem Karni, Eli Keshet, maxim mogilevsky, odelia shimshon, saran kumar, Eylon Yavin
modulation of mknk2 alternative splicing by splice switching oligonucleotides as a novel approach for glioblastoma treatment (2018)| Nucleic Acids Research| Read more
anna feldman, chani stossel, daniel yehuda, dikla atias, eitan friedman, ella buzhor, faridah mbabaali, ilinca lungu, john bartlett, julie wilson, Rotem Karni, keren cohen, maria raitsesgurevich, michael schvimer, Raanan Berger, robert denroche, sharon halperin, stephen raskin, steven gallinger, talia golan, yulia glick
recapitulating the clinical scenario of brca associated pancreatic cancer in pre clinical models (2018)| International Journal of Cancer| Read more
Rami Aqeilan, Ben Katz, Alexander Binshtok, Zvi Granot, janna michaeli, Rotem Karni, leonor cohendaniel, lola polyansky, maya gershkovitz, merav shaul, Ronit Vogt Sionov, saleh khawaled, Yoav Shaul, Shaya Lev, tanya fainsodlevi, Yaki Caspi, yasuo mori, zvi fridlender
trpm2 mediates neutrophil killing of disseminated tumor cells (2018)| Cancer Research| Read more
Rotem Karni, Zahava Siegfried
the role of alternative splicing in cancer drug resistance (2018)| Current Opinion in Genetics & Development| Read more
Rotem Karni, maxim mogilevsky, terese soudah, Eylon Yavin
clip6 pna peptide conjugates non endosomal delivery of splice switching oligonucleotides (2017)| Bioconjugate Chemistry| Read more
adi amarschwartz, itamar kozlovski, Rotem Karni, Zahava Siegfried
the role of rna alternative splicing in regulating cancer metabolism (2017)| Human Genetics| Read more
astridsolveig schultz, florian heyd, Rotem Karni, marco preussner, mario bunse
activation dependent traf3 exon 8 alternative splicing is controlled by celf2 and hnrnp c binding to an upstream intronic element (2017)| Molecular and Cellular Biology| Read more
alona rabner, Ron Dzikowski, Rotem Karni, lindsey altenhofen, manuel llinas, phil ross, shiri eshar, yael mandelgutfreund, yair fastman
pfsr1 controls alternative splicing and steady state rna levels in plasmodium falciparum through preferential recognition of specific rna motifs (2015)| Molecular Microbiology| Read more
long noncoding rna malat1 promotes hepatocellular carcinoma development by srsf1 upregulation and mtor activation ()| Cancer Research| Read more

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