Researcher interests: The effector functions of XBP-1 on the synthesis and breakdown of glycoproteins. Genes responsible for resistance to bortezomib, and their underlying mechanism of action.
FACULTY / SCHOOL: School of Medicine - IMRIC

Selected Publications

afshin samali, akram obiedat, chetan chintha, eric chevet, leif eriksson, michael huber, mohamed mahameed, odai darawshi, thomas schubert, thomas wilhelm, Boaz Tirosh, weisssadan tommy
the unfolded protein response modulators gsk2606414 and kira6 are potent kit inhibitors (2019)| Cell Death and Disease| Read more
akram obiedat, gad beck, jeffrey johnson, mohamed mahameed, Boaz Tirosh
low concentrations of cadmium chloride promotes protein translation and improve cell line productivity (2019)| Biotechnology and Bioengineering| Read more
akram obiedat, aristotelis chatziioannou, einat seidel, eric chevet, konstantinos voutetakis, Ofer Mandelboim, mari mcmahon, mohamed mahameed, orit berhani, pinchas tsukerman, Boaz Tirosh, tony avril
transcription of the nkg2d ligand mica is suppressed by the ire1 xbp1 pathway of the unfolded protein response through the regulation of e2f1 (2019)| The FASEB Journal| Read more
Galia Blum, Emmanuelle Merquiol, nadine hovelmeyer, naresh kumar meena, sandrine benhamron, saran kumar, shakti prasad pattanayak, Boaz Tirosh, yael bennun
mtorc1 activation in b cells confers impairment of marginal zone microarchitecture by exaggerating cathepsin activity (2018)| Immunology| Read more
Ann Saada, devorah yefet, erol cerasi, gil leibowitz, Tal Israeli, Boaz Tirosh, Yael Riahi
opposing effects of intracellular versus extracellular adenine nucleotides on autophagy implications for β cell function (2018)| Journal of Cell Science| Read more
behzad kharabimasouleh, fabian bick, john patterson, kerstin peters, michael huber, thomas wilhelm, Boaz Tirosh, vrinda mohta
infliction of proteotoxic stresses by impairment of the unfolded protein response or proteasomal inhibition as a therapeutic strategy for mast cell leukemia (2018)| Oncotarget| Read more
mohamed mahameed, Boaz Tirosh
engineering cho cells with an oncogenic kit improves cells growth resilience to stress and productivity (2017)| Biotechnology and Bioengineering| Read more
alik demishtein, ami navon, dikla berko, milana fraiberg, Boaz Tirosh, zvulun elazar
sqstm1 p62 mediated autophagy compensates for loss of proteasome polyubiquitin recruiting capacity (2017)| Autophagy| Read more
increasing the affinity of cationized polyacrylamide paclitaxel nanoparticles towards colon cancer cells by a surface recognition peptide (2017)| International Journal of Pharmaceutics| Read more
bantel, hubel, isabel zvibel, manns, noam erez, oren shibolet, raya cohen, roy avraham, sigal fishman, Boaz Tirosh
hepatic amiodarone lipotoxicity is ameliorated by genetic and pharmacological inhibition of endoplasmatic reticulum stress (2017)| Toxicological Sciences| Read more
aparna anand, baruch hertzog, cheng catherine youting, debabrata biswas, Emanuel Hanski, miriam ravins, Moshe Baruch, Boaz Tirosh
induction of endoplasmic reticulum stress and unfolded protein response constitutes a pathogenic strategy of group a streptococcus (2014)| Frontiers in Cellular and Infection Microbiology| Read more
Eli Breuer, Efrat Harel, Abraham Rubinstein, Boaz Tirosh, weibin chen
aminoalkylcarbamoylphosphonates reduce tnfα release from activated immune cells (2010)| Bioorganic & Medicinal Chemistry Letters| Read more

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