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Prof. Charles Jaffe

Researcher interests: Biochemistry and immunology of parasitic protozoa leishmaniasis. Development of vaccines and diagnostic test for visceral leishmaniasis. The role of protein kinases in development of the parasite.
FACULTY / SCHOOL: School of Medicine - IMRIC
Contact Business Development: Keren-Or Amar
Microbiology (24)Molecular genetics (14)

Selected Publications

abdelmajeed nasereddin, bettina moser, caroline durrant, charles l jaffe, Gabriele Schönian, henk d f h schallig, hideo imamura, isabel mauricio, Charles Jaffe, james cotton, jeanclaude dujardin, l f schnur, mandy sanders, matthew berriman, matthew yeo, michael a miles, mohammad zahangir alam, olivia stark, susanne u franssen, tapan bhattacharyya, thierry wirth, tim downing
global genome diversity of the leishmania donovani complex (2019)| bioRxiv| Read more
Abedelmajeed Nasereddin, aviv barzilai, charles l jaffe, eli schwartz, felix pavlotzky, Charles Jaffe, michal solomon, nadav sahar
mucosal leishmaniasis in travelers with leishmania braziliensis complex returning to israel (2019)| Emerging Infectious Diseases| Read more
asrat hailu, charles l jaffe, f pratlong, hanan t jaber, Charles Jaffe, patrick bastien, patrick lami
analysis of genetic polymorphisms and tropism in east african leishmania donovani by amplified fragment length polymorphism and kdna minicircle sequencing (2018)| Infection, Genetics and Evolution| Read more
ada yonath, anat bashan, charles l jaffe, donna matzov, ella zimmerman, georgios skiniotis, haim rozenberg, Charles Jaffe, masato taoka, moran shalevbenami, toshiaki isobe, yan zhang, yuko nobe
atomic resolution snapshot of leishmania ribosome inhibition by the aminoglycoside paromomycin (2017)| Nature Communications| Read more
aldert bart, carmen chicharro, charles l jaffe, christophe ravel, felix grimm, florence robertgangneux, gert van der auwera, gundel harms, ingrid felger, jaco j verweij, Charles Jaffe, jeanclaude dujardin, jeroen roelfsema, leigh davidsson, maria grazia paglia, monika m manser, peter l chiodini, Seray Özensoy Töz, sofia cortes, trentina di muccio
comparison of leishmania typing results obtained from 16 european clinical laboratories in 2014 (2016)| Eurosurveillance| Read more
ada yonath, anat bashan, arie zackay, charles l jaffe, donna matzov, ella zimmerman, georgios skiniotis, haim rozenberg, Charles Jaffe, moran shalevbenami, y halfon, yan zhang
2 8 a cryo em structure of the large ribosomal subunit from the eukaryotic parasite leishmania (2016)| Cell Reports| Read more
Abedelmajeed Nasereddin, charles l jaffe, dmitry kopelyanskiy, Charles Jaffe, jari ylikauhaluoma, kirsimarja oksmancaldentey, marcel kaiser, minni pirttimaa, reto brun, sami alakurtti, vânia m moreira
abietane type diterpenoid amides with highly potent and selective activity against leishmania donovani and trypanosoma cruzi (2016)| Journal of Natural Products| Read more
abdelmajeed nasereddin, charles l jaffe, Charles Jaffe, jari ylikauhaluoma, marcel kaiser, mikko vahermo, reto brun, sara krogerus, vânia m moreira
antiprotozoal activity of dehydroabietic acid derivatives against leishmania donovani and trypanosoma cruzi (2016)| MedChemComm| Read more
charles l jaffe, haim rozenberg, Charles Jaffe, moran shalev, noam adir, timor baasov
paromomycin bound to a leishmanial ribosomal a site (2015)| | Read more
Abedelmajeed Nasereddin, antti siiskonen, charles l jaffe, dmitry kopelyanskiy, Charles Jaffe, jari ylikauhaluoma, leena keurulainen, nina sacerdotisierra, paivi tammela, paula kiuru, teppo o leino
synthesis and biological evaluation of 2 arylbenzimidazoles targeting leishmania donovani (2015)| Bioorganic & Medicinal Chemistry Letters| Read more

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