Researcher interests: Protein design: protein-protein interactions; developing methods for the design of protein binding interfaces.
FACULTY / SCHOOL: Faculty of Science
Selected Publications
generating quantitative binding landscapes through fractional binding selections deep sequencing and data normalization (2019)|
bioRxiv|
Read more
allosteric modulation of binding specificity by alternative packing of protein cores (2019)|
Journal of Molecular Biology|
Read more
converting a broad matrix metalloproteinase family inhibitor into a specific inhibitor of mmp 9 and mmp 14 (2018)|
FEBS Letters|
Read more
analysis of structural features contributing to weak affinities of ubiquitin protein interactions (2017)|
Journal of Molecular Biology|
Read more
editorial overview engineering and design new trends in designer proteins (2017)|
Current Opinion in Structural Biology|
Read more
development of high affinity and high specificity inhibitors of matrix metalloproteinase 14 through computational design and directed evolution (2017)|
Journal of Biological Chemistry|
Read more
identifying residues that determine scf molecular level interactions through a combination of experimental and in silico analyses (2017)|
Journal of Molecular Biology|
Read more
cold spots in protein binding (2016)|
Trends in Biochemical Sciences|
Read more
saturation scanning of ubiquitin variants reveals a common hot spot for binding to usp2 and usp21 (2016)|
Proceedings of the National Academy of Sciences of the United States of America|
Read more
protein engineering by combined computational and in vitro evolution approaches (2016)|
Trends in Biochemical Sciences|
Read more
