Researcher interests: Joint diseases caused by cartilage degeneration. Regeneration and repair of damaged cartilage. Chromatin biology and gene expression in chondrocytes (diseased and healthy). The role of SirT1 and other chromatin-modifying enzymes in inflammatory arthritis.
FACULTY / SCHOOL: Faculty of Dental Medicine
DEPARTMENT: Institute of Dental Sciences
Selected Publications
sirt1 cleavage from cartilage degeneration to osteoarthritic biomarker (2019)|
Osteoarthritis and Cartilage|
Read more
a predicted unstructured c terminal loop domain in sirt1 is required for cathepsin b cleavage (2018)|
Journal of Cell Science|
Read more
lymphoid enhancer binding factor 1 mediated matrix metalloproteinase 13 gene expression is repressed by sirt1 in human chondrocytes (2018)|
Osteoarthritis and Cartilage|
Read more
chondrocyte secretome a source of novel insights and exploratory biomarkers of osteoarthritis (2017)|
Osteoarthritis and Cartilage|
Read more
lef1 mediated mmp13 gene expression is repressed by sirt1 in human chondrocytes (2017)|
The FASEB Journal|
Read more
a chronic low dose of delta 9 tetrahydrocannabinol thc restores cognitive function in old mice (2017)|
Nature Medicine|
Read more
sox9 and the many facets of its regulation in the chondrocyte lineage (2017)|
Connective Tissue Research|
Read more
the role of sirtuins in cartilage homeostasis and osteoarthritis vol 18 43 2016 (2016)|
|
Read more
acetylation reduces sox9 nuclear entry and acan gene transactivation in human chondrocytes (2016)|
Aging Cell|
Read more
nad dependent deacetylases and medical therapy (2016)|
Medical Epigenetics|
Read more