Researcher interests: Aging regulating signaling pathways, in particular the Insulin/IGF pathway. Molecular and cell biology of the aging process. Mechanistic links that couple aging and toxic protein aggregation.
FACULTY / SCHOOL: School of Medicine - IMRIC
DEPARTMENT: Biochemistry and Molecular Biology
Selected Publications
expanded cug repeats trigger disease phenotype and expression changes through the rnai machinery in c elegans (2019)|
Journal of Molecular Biology|
Read more
gene expression modulation by the linker of nucleoskeleton and cytoskeleton complex contributes to proteostasis (2019)|
bioRxiv|
Read more
the insulin igf signaling cascade modulates sumoylation to regulate aging and proteostasis in caenorhabditis elegans (2018)|
eLife|
Read more
modulation of caveolae by insulin igf 1 signaling regulates aging of caenorhabditis elegans (2018)|
EMBO Reports|
Read more
self assembly of a metallo peptide into a drug delivery system using a switch on displacement strategy (2018)|
Journal of Materials Chemistry B|
Read more
a multi animal tracker for studying complex behaviors (2017)|
BMC Biology|
Read more
vesicle mediated secretion of misfolded prion protein molecules from cyclosporin a treated cells (2017)|
The FASEB Journal|
Read more
protein quality control in health and disease (2017)|
Cold Spring Harbor Perspectives in Biology|
Read more
the emerging roles of early protein folding events in the secretory pathway in the development of neurodegenerative maladies (2017)|
Frontiers in Neuroscience|
Read more
from mutated genes to familial alzheimer s disease ()|
Cell Cycle|
Read more
