Researcher interests: Pain is a major unmet medical need that has reached pandemic scale, causing extensive personal suffering and costing hundreds of billions of dollars every year in medical expenses and lost productivity. Lack of adequate understanding of the mechanisms of
FACULTY / SCHOOL: School of Medicine - IMRIC
DEPARTMENT: Medical Neurobiology
Selected Publications
platelet derived growth factor activates nociceptive neurons by inhibiting m current and contributes to inflammatory pain (2019)|
Pain|
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location and plasticity of the sodium spike initiation zone in nociceptive terminals in vivo (2019)|
Neuron|
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differential cytotoxicity and intracellular calcium signalling following activation of the calcium permeable ion channels trpv1 and trpa1 (2017)|
Cell Calcium|
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ultrafast optical recording reveals distinct capsaicin induced ion dynamics along single nociceptive neurite terminals in vitro (2017)|
Journal of Biomedical Optics|
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the role of kv7 m potassium channels in controlling ectopic firing in nociceptors (2017)|
Frontiers in Molecular Neuroscience|
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privileged crosstalk between trpv1 channels and mitochondrial calcium shuttling machinery controls nociception (2016)|
Biochimica et Biophysica Acta|
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quaternary lidocaine derivative qx 314 activates and permeates human trpv1 and trpa1 to produce inhibition of sodium channels and cytotoxicity (2016)|
Anesthesiology|
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multispectral labeling technique to map many neighboring axonal projections in the same tissue (2015)|
Nature Methods|
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the role of slow and persistent ttx resistant sodium currents in acute tumor necrosis factor α mediated increase in nociceptors excitability (2015)|
Journal of Neurophysiology|
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