Researcher interests: Malaria parasites, Plasmodium falciparum; mechanisms that regulate gene expression that support the parasite ability to evade the immune system. The role of nuclear architecture in regulation of gene expression. Alternative splicing in P. falciparum.
FACULTY / SCHOOL: School of Medicine - IMRIC
DEPARTMENT: Microbiology and Molecular Genetics
Selected Publications
an upstream open reading frame uorf signals for cellular localization of the virulence factor implicated in pregnancy associated malaria (2018)|
Nucleic Acids Research|
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antiplasmodial dihetarylthioethers target the coenzyme a synthesis pathway in plasmodium falciparum erythrocytic stages (2017)|
Malaria Journal|
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controlled release of artemisone for the treatment of experimental cerebral malaria (2017)|
Parasites & Vectors|
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variant gene expression and antigenic variation by malaria parasites (2017)|
Annual Review of Microbiology|
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adhesion of plasmodium falciparum infected erythrocytes in ex vivo perfused placental tissue a novel model of placental malaria (2016)|
Malaria Journal|
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novel 2 phenoxyanilide congeners derived from a hit structure of the tcams synthesis and evaluation of their in vitro activity against plasmodium falciparum (2016)|
Molecules|
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multiple plasmodium falciparum erythrocyte membrane protein 1 variants per genome can bind igm via its fc fragment fcμ (2015)|
Infection and Immunity|
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pfsr1 controls alternative splicing and steady state rna levels in plasmodium falciparum through preferential recognition of specific rna motifs (2015)|
Molecular Microbiology|
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functional analysis of sirtuin genes in multiple plasmodium falciparum strains (2015)|
PLOS ONE|
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antisense long noncoding rnas regulate var gene activation in the malaria parasite plasmodium falciparum (2015)|
Proceedings of the National Academy of Sciences of the United States of America|
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