Researcher interests: Stem cells, Cellular reprogramming and transdifferentiation. The role of the immediate response gene ATF3 in cancer. Utilization of single-cell techniques to decipher the molecular mechanism of somatic cell reprogramming to pluripotency.
FACULTY / SCHOOL: School of Medicine - IMRIC
DEPARTMENT: Developmental Biology and Cancer Research
Selected Publications
Direct Induction of the Three Pre-implantation Blastocyst Cell Types from Fibroblasts (2019)|
Cell Stem Cell.|
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Extensive Nuclear Reprogramming Underlies Lineage Conversion into Functional Trophoblast Stem-like Cells (2015)|
Cell Stem Cell|
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mutant p53r273h attenuates the expression of phase 2 detoxifying enzymes and promotes the survival of cells with high levels of reactive oxygen species (2012)|
Journal of Cell Science|
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Single-cell expression analyses during cellular reprogramming reveal an early stochastic and a late hierarchic phase (2012)|
Cell|
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