Sensitizing hematopoietic malignancies to genotoxic treatment by targeting APOBEC3G
Categories
Cancer
Development Stage
Feasibility established in lymphoma cell lines
Patent Status
Provisional application filed
Market
Hematopoietic ...
Splicing factor levels predict patient prognosis and indicate drug efficacy
Categories
Oncology/Cancer, RNA/Protein/Diagnosis, Biomarkers
Development Stage
Proof of concept in vitro and in small animals
Patent Status
Patent filed in the ...
Self targeting to the extracellular fluid gives ideal drugs
Categories
Cancer, metastasis, drug, zinc enzyme inhibitor
Development Stage
Drug at preclinical stage
Patent Status
PCT published (WO2010/089752)
Market Size
Global oncology ...
Once-daily, sustained-release Sirolimus delivery system
Categories
Oral Cavity, Oncology/Cancer, Sustained Release, Drug Delivery
Development Stage
Prototypes tested in vitro; pharmokinetic and pharmacodynamic testing in human volunteers ...
Additional material on the technology can be supplied upon request
Results in mouse and human cell models validate approach
Categories
Ceramide, apoptosis, cancer, sphingolipids, prostate cancer
Development Stage
Considerable anticancer activity in vivo in prostate, colon, pancreas and melanoma mouse ...
Department of Microbiology and Molecular Genetics, Faculty of Medicine, ophryp@ekmd.huji.ac.il, 972-2-675-7203
IMRIC
Institute for Medical Research Israel-CanadaResearch Hub Goals and Activities
To develop collaborations with industry ...
Less toxic quinonoid derivatives of cannabinoids
Categories
Oncology/Cancer, Formulation, New Chemical Entity
Development Stage
Proof of concept in vitro
Patent Status
Patent filed in the U.S. and Europe (PCT publication no: WO ...
Coordinator: Dr. Ittai Ben PorathDepartment of Developmental Biology and Cancer Research, Faculty of Medicine, ittaibp@cc.huji.ac.il, 972-2-675-7006
Co-coordinators: Professor Tamar Peretz, Director, Sharett Institute for Oncology, Hadassah ...
New approaches to developing reagents that block cancers' support mechanism
Categories
Life Sciences and Biotechnology, MedicineProfessor Ben Neriah's Laboratory for Immunology and Cancer Research, The Lautenberg Center for General and Tumor ...
Novel approach inactivates transporter protein from within the cell
Categories
Oncology/Cancer Treatment
Development Stage
Proof of concept in tissue culture
Patent Status
Provisional patent filed in the United States
Market Size
Over 70 ...
Liposomes carrying combinations of drugs for improved results
Categories
Drug Delivery, Oncology / Cancer
Development Stage
Pre-clinical trials almost complete
Patent Status
Patent publication number WO/2006/051549; filed in US, IL, CA, ...
Antibodies from mouse lymphoma cells recognize human breast cancer
Categories
Oncology, breast cancer diagnosis and treatment, antibodies
Development Stage
Positive results obtained in mice and in small number of human samples
Patent ...
Genetic material encapsulated in polymeric nanoparticles
Categories
Drug delivery, nanotechnology, nanoencapsulation
Development Stage
Proof of concept in vitro and in vivo
Patent Status
US and PCT applications filed
Market ...
Gene expression data helps to improve diagnostics, therapeutic approach
Categories
Oncology software, cancer diagnosis, personalized medicine
Development Stage
Working prototype
Patent Status
U.S. patent application filed
Market ...
A Novel Preparation Method of Cationic Building Blocks for Gene-Scilencing Molecules
Category
Anti-gene and anti-sense drug development
Development Stage
Technology up-scale and enhancement
Patent Status
Patent Pending
Market Size
Market ...