New pathway to reduce toxicity of α-Synuclein
Categories
Parkinson’s disease, α-Synuclein, Brain lipids
Development Stage
Proof of concept demonstrated
Patent Status
Provisional patent application filed
Market
Parkinson’s Disease is a ...
Anti-CD48 agent blocks CD48 stimulatory pathway and inhibits the activity and expression of CD48
Categories
Drugs, Allergic airway inflammations, Asthma
Development Stage
Laboratory and animal trials were performed
Patent Status
Patent ...
Liposomes as a Novel Bio-lubricant for Osteoarthritic Joints
Investment/ Collaboration Opportunity Highlights:
Having recently completed a successful proof-of-concept clinical trial, at December 2012, the company plans to launch a pivotal ...
For more information read in:
http://www.cs.huji.ac.il/~ynahmias/Microliver_Laboratory/Research.html
Investment/ Collaboration Opportunity Highlights:
Raziel therapeutics was founded in 2012 and raised money from privet leader investors in round A.
About the company
Raziel therapeutics is innovative company dedicated to address unmet needs ...
Developing a new generation of anti-inflammatory drugs
Investment/ Collaboration Opportunity Highlights:
Investment round: Morria is currently in the process of completing a financing round coupled with a listing on a public exchange in the ...
C-arm-mounted device reduces number of X-rays
Categories
Bone/Cartilage, Imaging, Image Guided Surgery, Medical Applications
Development Stage
Prototype, successful trials on medical mannequins
Patent Status
Patent filed in Israel, US and ...
miRNA signature for diagnosis and indication of responsiveness to therapy
Categories
Oncology, Pediatrics, Diagnostics
Development Stage
Diagnostic- Clinical POC; Therapeutic-pre-clinical
Patent Status
Provisional patent application ...
Categories
Medical Imaging, Oral Medicine, Quantification of lesion color change
Patent
US 2008/0260218 A1Need:
In current practice of dermal analysis and of oral and dental lesion analysis, the physician typically observes the suspected ...
Novel approach using low molecular weight antioxidants
Categories
CNS, Cardiovascular, Inflammation, NAC-amide (AD4)
Development Stage
Successful toxicology studies completed for AD4
Patent Status
Patents filed in Australia and United ...
Categories
Regeneration of: Ligament, Tendon, Cartilage, Periodontium, Muscle, Bone.
Mesenchymal Stem cells, Amelogenin (rHAM+), Recombinant Peptide/Protein
Development Stage
Ongoing research
Patent Status
PCT filedHighlights
Trauma or ...
Delivers treatment in response to pH conditions in mouth
Categories
Coatings, Biomaterials, Polymers, Composites, Dental Care
Development Stage
Successful clinical trials – ready for commercialization
Patent Status
Patent pending
Market ...
A valid predictive marker for non-transmitters
Categories
CMV infection, Diagnostics, Biomarkers
Development Stage
Proof of conceptHighlights
Fetal infection with Cytomegalovirus (CMV) is the most common intrauterine infection in the ...
Categories
Peptide, Oncology/Cancer, Small molecule
Development Stage
Proof of concept
Patent Status
Provisional patent application filed
Market
Cancer therapy
Highlights
p53, the most important tumour suppressor protein in the cell, is ...
Transgenic tobacco plants developed to produce artemisinin
Categories
Transgenic plants, Infectious diseases, Anti-cancer, Drug synthesis
Development Stage
Proof of concept. Biosynthesis system prototype
Patent Status
United States patent ...
Antigen and/or organic adjuvant entrapped within alumina adjuvant
Categories
Antibodies, Vaccinations, Drug delivery, Immunology, Adjuvants, Alumina
Development Stage
In vivo proof of concept
Patent Status
Provisional patent filed in the ...
Leads to better outcomes for liver resection
Categories
Oncology / Cancer, Small molecule, Peptide / Protein
Development Stage
Proof of concept – initial animal trials in mice
Patent Status
International patent published
Market
The liver ...
Fills the gap between crystallography and optical imaging
Categories
Computer Science & Engineering , Chemistry & Materials, Life Science & Biotechnology, Research / Development tools, Computational Biology, Peptide / ...
Sensitizing hematopoietic malignancies to genotoxic treatment by targeting APOBEC3G
Categories
Cancer
Development Stage
Feasibility established in lymphoma cell lines
Patent Status
Provisional application filed
Market
Hematopoietic ...
Human embryonic stem cell lines derived from Pre-Implantation Genetic Diagnosis (PGD) embryos
Categories
Mutant Human Embryonic Stem Cells , drug screening, genetic disordersStem Cell Research Laboratory, Medical Genetics Institute, Shaare ...
Novel treatment for Parkinson’s disease overcomes “on-off” phenomenon
Categories
Parkinson’s disease, L-dopa, L-dopa amide
Development Stage
Concept proven, in vivo human models
Patent Status
Pending patent application in, Europe, US ...
Short peptide includes the functional segment of RA-specific protein
Categories
Peptide/Protein, Inflammation, Autoimmunity
Development Stage
Feasibility demonstrated in mouse models
Patent Status
Provisional application filed
Market ...
An inexpensive method for laboratory growth of anaerobic bacteria, replacing traditional anaerobic chambers and jars and allowing small-scale growth of bacterial cultures in various types of laboratory plates and test tubes. It also enables ...
HU-436 reduces weight and food consumption in mice
Categories
Phytotherapy, Synthetic derivatives of Cannabis components
Development Stage
Weight reduction demonstrated in three animal models
Patent Status
Provisional patent application ...
Enables in situ delivery of active ingredients where and when required
Categories
Veterinary Medicine /Animal Science , Human Medicine, Life Science & Biotechnology, Veterinary Formulations, Medical device, Dental
Development ...
Enables detection from 15-17th week of pregnancy
Categories
Antibodies, Diagnostics
Development Stage
Proof of concept in human placentas
Patent Status
Patents filed US and Japan Israel, Europe and Canada
Market Size
2004 musculoskeletal ...
Splicing factor levels predict patient prognosis and indicate drug efficacy
Categories
Oncology/Cancer, RNA/Protein/Diagnosis, Biomarkers
Development Stage
Proof of concept in vitro and in small animals
Patent Status
Patent filed in the ...
Alternative to Morris water maze for aquatic and other animals
Categories
Research/Development tools, Neurobehavior
Development Stage
Prototype developed for zebrafish
Patent Status
Provisional patent application filed
Market ...
Self targeting to the extracellular fluid gives ideal drugs
Categories
Cancer, metastasis, drug, zinc enzyme inhibitor
Development Stage
Drug at preclinical stage
Patent Status
PCT published (WO2010/089752)
Market Size
Global oncology ...
Categories
Biotechnology- Diagnosis, Homeland Security
Development Stage
Proof of concept established; seeking commercial partner
Patent Status
Patent applied for in Us. Europe, Canada, Australia, Israel and Singapore
Market Size
About ...