Splicing Modulation as a treatment for cancer or metabolic diseases

Karni Rotem, HUJI, School of Medicine - IMRIC, Biochemistry and Molecular Biology


Life Sciences and Biotechnology   


Oncology, Breast Cancer, Splicing Modulation, Metabolic Diseases

Unbalanced alternative splicing of specific genes is present in several diseases including diabetes and cancer, and more precisely breast cancer. Small molecules or antisense oligonucleotide technology that can restore the normal splicing balance, can also inhibit cancer development and progression. 

Our innovation
Our technology is a new approach to diagnosis and the treatment of certain human breast cancers. We develop small molecules of antisense oligonucleotide that modulate gene splicing for the treatment of cancer where this gene’s splicing is abnormal.

Our innovation opens, for the first time, the possibility of a vaccine against breast cancers.


Contact for more information:

Ariela Markel
VP, Business Development, Healthcare
Contact ME: