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Research & Services | Traumatic Brain Injury Laboratory

Prof. Shohami Esther, HUJI, School of Medicine - IMRIC, School of Pharmacy- Institute for Drug Research

Categories

Neuroscience, neurology, traumatic brain injury (TBI)

Objective/function

  • The laboratory is active in the study and treatment of traumatic brain injury (TBI)

Research provided

  • Study of pathophysiology and basic mechanisms of neuroprotection and repair; development of potential novel therapeutic agents and strategies    
  • Testing compounds developed by others for their potential neuroprotective effect in a well-established model of traumatic brain injury in mice

Advantages

  • The animal model developed and widely studied in our lab for focal TBI serves as a platform for pre-clinical testing of potential drugs. We have a battery of neurobehavioral, motor and cognitive tests to assess the functional outcome after TBI and the effects of therapeutic intervention or genetic manipulations (e.g. transgenic o knockout mice)

Client record

  • Performed assessments of drugs for Pharmos, SK&B, Serono, Teva, and Bayer

Available equipment

  • Device to produce closed head injury
  • Set-up for evaluation of cognitive (object recognition test), behavioral (forced swimming test), and motor functions

Staff

  • Alexander Alexandrovich, MD
  • Victoria Trembovler, PhD

Contact for more information:

Itzik Goldwaser
VP, Head of Research Collaborations
+972-2-6586685
Contact ME:
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