Hydrocolloid Carriers with Filler Material

Nussinovitch Amos, HUJI, Faculty of Agricultural, Food and Environmental Quality Sciences, Biochemistry, Food Science and Nutrition
Gal Avi, HUJI, Faculty of Agricultural, Food and Environmental Quality Sciences, Biochemistry, Food Science and Nutrition

Improved controlled-release capsules


Agriculture, Food and Nutrition, Materials, Pest Control / Herbicides, Carriers / Encapsulation, Biodegradable, Hydrocolloids, Slow Release

Development Stage

Proof of concept; additional research underway

Patent Status

Patent pending in the US

Market Size

Global nutraceuticals market projected to reach $74.7 billion by 2007 with AAGR 9.9%; Flavors and fragrance ingredient market approximately $6.3 billion, 2006; Global pesticide industry estimated at $26 billion; biological pest control expected to grow to $4 billion by 2015.


  • Composite carriers (capsules) with improved mechanical properties
  • Inert filler material improves carrier properties and controls release rate of bioactive components
  • Controlled release of agents used in pest control, herbicides, and fertilizers; active agents in food industry
  • Preparation of carriers for embedding nutraceuticals such as vitamins, preservatives, pigments, and flavor enhancing compounds; active agents in chemical industries and biotechnology

Our Innovation

Technology has proven advantages over other sustained release formulations because varied structure of the carriers enable adjustable rate of release of active agent

Key Features

  • Capsule size tailored from 500 microns to 4 mm
  • Control of mechanical properties
  • Stable in assorted environments; shelf life for carriers (after drying) at least two years
  • Simple, low-cost preparation
  • Meets prevailing production standards in, agricultural, food, and biotechnology industries

Development Milestones

  • Proof of concept
  • Yissum seeks licensing agreements, strategic partnerships, or joint ventures for commercialization

The Opportunity

  • Potential to create new applications and markets including cosmetics, toiletries, and packaging


  • Electron micrographs of halved freeze-dried carriers. Alginate carriers
    (X350) without filler (A) and with fillers (B–F: calcium carbonate, corn starch, kaolin,
    potato starch, talc, respectively).

Patent Status

Granted US 8,932,634

Contact for more information:

Amichai Baron
VP, Head of Business Development, Agritech & Envir
Contact ME: