Projects related to 6-2016-4294

Results Found (13)
Technology NameBriefcaseLead Researcher
Background        Chicken embryonic fibroblasts (CEFs) are commonly used for the production of vaccines and are a source material for cultured meat. Fibroblasts are contact-dependent limiting their large-scale production to carrier beads capable ...
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Nahmias Yaakov
Background Recurrent miscarriage, preeclampsia and intra-uterine growth restriction (IUGR) are three common implantation (placental)-related diseases and a major cause of mortality and morbidity for mother and child, complicating between 3 to 10 ...
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Buganim Yossi
Our Innovation   The finding by HUJI researchers uncovers a novel structure of an outer mitochondrial membrane [Fe-S] protein (mitoNEET) determined by X-ray crystallography (Fig 1)  MitoNEET is an outer mitochondrial membrane protein that ...
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Nechushtai Rachel
  Categories Superactive High Afinity Leptin antagonist, mutein, multiple sclerosis, inflammatory bowel syndrome, rheumatoid arthritis, fibrosis, cardiovascular disease, CKD Cachexia, Osteoarthritis Development Stage (1) In vivo tests in ...
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Gertler Arieh
Yousef Najajreh, Al Quds University   Background A growing number of peoples worldwide are suffering from the health consequences of obesity. As for today, Only one drug is currently approved for long-treatment of obesity-the lipase ...
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Avraham Yosefa
Prof. Yaron Ilan, Department of Human Nutrition and Metabolism and Liver Unit Hadassah Hospital Background To date, there is no effective treatment of liver diseases with the related Hepatic-Encephalopathy symptoms. It is established that ...
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Avraham Yosefa
  Our Innovation   Based on a provocative working hypothesis, we most probably identified the molecular origin of insulin resistance (IR). Systemic IR is induced via post-translational modification (PTM) of liver key regulatory proteins. We ...
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Ben-Sasson Shmuel
  Categories Small molecules, anti-inflammatory treatment Development Stage In-vivo proof of concept Patent Status Patent application filed Market Inflammation indications: acute pancreatitis, acute live damage, fatty liver damage, ...
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Weinstock-Rosin Marta
Background Hyperlipidemia is a widespread condition that affects as many as one-third of adults and an increasing number of children in developed countries. Its pathogenesis mechanisms are only partly understood. The small non-coding microRNAs ...
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Soreq Hermona
  Background Non-alcoholic fatty liver disease (NAFLD) and associated diseases Non-alcoholic steatohepatitis (NASH), Cirrhosis, and Hepatocellular carcinoma (HCC) cost the US economy an estimated at $103 billion per year. Lipotoxicity is a major ...
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Tirosh Oren
  Category Life Sciences and Biotechnology    Keywords Metabolic Syndrome, Transfer RNA fragments, Fatty liver disease, Diagnostics, Antisense oligonucleotide therapeutics, Biomarkers, Hepatic hyperlipidemia Current development stage For ...
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Soreq Hermona
Categories: Life sciences and Biotechnology Technology Keywords: Drug Development, PPARD, Obesity, Glycogen Preserving, Lipid Metabolism, Wound Healing Development Stage: In silico, Identification of lead molecules, in vitro ...
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Goldblum Amiram
BackgroundAccording to the World Health Organization approximately 422 million people currently suffer from diabetes. Type-I diabetes patients are characterized by their pancreas β-cells dysfunction and thereby absence of insulin secretion. ...
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Willner Itamar