Projects related to 6-2017-4492

Results Found (26)
Technology NameBriefcaseLead Researcher
Delivers treatment in response to pH conditions in mouth   Categories Coatings, Biomaterials, Polymers, Composites, Dental Care Development Stage Successful clinical trials – ready for commercialization Patent Status Patent ...
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Friedman Michael
  Background Current methods of tissue fixation leave much to be desired, essentially relying on technologies developed from the clothing and carpentry industries i.e. sutures, screws, and pins. Bioadhesives offer a less traumatic method of ...
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Mandler Daniel
Keywords Drug Delivery, Formulation Current development stage TRL7, Prototype and proprietary list of approved drugs that benefit from liposomal formulationsApplication Most active pharmaceutical ingredients (APIs) are not suitable for ...
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Goldblum Amiram
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Avraham Yosefa
Keywords Nanoparticles, Neuropeptides, Intranasal delivery Current development stage TRL4 - POC & Safety of candidate drug formulation is demonstrated in defined animal model Highlights Emulsification in aqueous media is not effective ...
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Domb Abraham
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Domb Abraham
  Categories: Life Science & Biotechnology Technology Keywords: Formulation, drug delivery, increased bioavailability Development Stage: POC in animalOur Innovation The PNL formulation composed of GRAS materials enabling ...
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Domb Abraham
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Domb Abraham
Category Life Sciences and Bio Technology    Keywords Chemotherapy, Drug resistance * The project is conducted in collaboration with Memorial Sloan-Kettering Cancer Center. Application Cells with multidrug resistance (MDR) due to aberrant ...
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Barenholz Yechezkel
Background Peptides are key players in a variety of physiological and pathological processes and play very important roles in modulating various cell functions. One of the most important challenges developing peptide drugs is the lack of ...
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Gilon Chaim
  Background With advances in biotechnology, nasal drug delivery is increasingly becoming a more viable alternative to oral and injectable routes of administration for an increasing number of drugs, including peptides. Our Innovation Platform ...
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Touitou Elka
Background Age-Related Macular Degeneration (AMD) and Diabetic Retinopathy (DR) are leading causes of blindness in the Western world. Both are characterized by pathological angiogenesis in the various eye structures. With high prevalence  in  ...
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Willner Itamar
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Domb Abraham
Category LifeSciences and BioTechnology    Keywords Therapeutic Agents, Liposomes, Biochemistry, Doxorubicin, Sulfate, Alkyl Sulfonate, DoxilTM  Application Current preclinical and clinical data indicate that there is negligible release of ...
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Barenholz Yechezkel
  Category Life Sciences and Bio Technology    Keywords Nanoparticles, Neuropeptides, Intranasal delivery Current development stage TRL4 - POC & Safety of candidate drug formulation is demonstrated in defined animal modelHighlights ...
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Domb Abraham
Background Conventional manufacturing of pharmaceutical dosage forms (e.g. tablets, capsules) are typically restricted to certain designs and materials and are commonly being used in a generic form of tablets or capsules with or without enteric ...
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Magdassi Shlomo
Category Life Sciences and Biotechnology    Keywords Carriers, Cathepsin proteases, Tetra-peptides Current development stage TRL4 - POC & Safety of candidate drug formulation is demonstrated in defined animal model Application The ...
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Blum Galia
Background Multiple strategies exist for the targeted treatment of different cell pathologies. One ongoing challenge is the introduction of therapeutic molecules into cells. Current approaches rely on viral vectors, electroporation, or carriers. ...
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Shenhar Roy
Categories: Life Science & Biotechnology Technology Keywords: Nasal administration, CNS active oil,  neurodegenerative diseases, CNS Development Stage: Formulation and experiments in animals Patent Status: US  patent application ...
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Touitou Elka
Once-daily, sustained-release Sirolimus delivery system Categories Oral Cavity, Oncology/Cancer, Sustained Release, Drug Delivery Development Stage Prototypes tested in vitro; pharmokinetic and pharmacodynamic testing in human volunteers ...
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Friedman Michael
Background The physical size of protein drugs and their susceptibility to degradation are key determinates that make them more dependent on drug delivery technologies. However formulating protein delivery systems so that they maintain their ...
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Barenholz Yechezkel