Projects related to 7-2006-115

Results Found (55)
Technology NameBriefcaseLead Researcher
Validated approach in small animals and human cell models   Categories Ceramide, apoptosis, cancer, sphingolipids, prostate cancer Development Stage Considerable anticancer activity in vivo in prostate, colon, pancreas and melanoma mouse ...
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Dagan Arie
  Categories Superactive High Afinity Leptin antagonist, mutein, multiple sclerosis, inflammatory bowel syndrome, rheumatoid arthritis, fibrosis, cardiovascular disease, CKD Cachexia, Osteoarthritis Development Stage (1) In vivo tests in ...
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Gertler Arieh
A specific therapy for treating this serious disease   Categories Mastocytosis, Cancer Development Stage Proof-of-concept, preclinical Patent Status Patent Pending Market Mastocytosis, Mast Cell Leukemia, AllergiesBackground Mast cells ...
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Levi-Schaffer Francesca
Categories Oncology, Cancer, Diagnostics Development Stage In vitro proof of concept and small animals Patent Status PCT application filed Market Cancer testing is currently one of the most important growth opportunities diagnostics ...
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Karni Rotem
  Categories: Life science and biotechnology Technology Keywords: Oncology, cancer drug resistance , chemotherapy, prodrug Development Stage: Preliminary POC with supporting in-vivo data Application Although FDA approved Pt(II) drugs are ...
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Gibson Dan
The Application Most cancers are unstable and highly susceptible to cell death; hence tumors represent a steady-state picture of unregulated proliferation as well as ongoing cell death. Therefore, substantial levels of tumor specific DNA may be ...
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Hellman Asaf
  Categories Diagnostics,  Research Development Stage In vitro and in-vivo proof of concept; ongoing research Patent Status US, Europe and China applications filed based on WO 2017/025968  Background Fluorescence guided surgery is currently ...
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Yavin Eylon
Category Life Sciences and Biotechnology    Keywords Tumor, Digestive System, Microwave, Ablation, Cancer, Radiation Current development stage TRL2 - Hypothesis testing and initial POC;  ex-vivo    Application        Very small tumors ...
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Feldman Yuri
  Category Life Sciences and Biotechnology    Keywords Cathespin, Molecular Imaging, Cancer, CT, Computed Tomography, Current development stage TRL3 - Hypothesis testing and initial POC demonstrated in-vivo Application X-ray computed ...
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Blum Galia
  Categories Treatment of cancer, neurodegeneration and infectious diseases. Development Stage In vitro proof of concept; in vivo POC Patent Status PCT publication number : WO2016/142948Highlights A new technology to inhibit the activity ...
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Karni Rotem
Keywords Cancer, Peptide, NAF-1 Current development stage Initial in-vivo studies completed Application It was recently shown that enhanced expression of NAF-1, is associated with different cancers, including breast, prostate, gastric, ...
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Nechushtai Rachel
  Category Medical Sciences, Stem cells, Small molecules Our Innovation Improved removal of PSCs may be obtained by identifying small molecules that selectively perturb crucial pathways in PSCs, and thus induce cell death in these cells ...
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Benvenisty Nissim
  Category Medical SciencesHighlights Epigenome editing by DNA methylation or demethylation of regulatory sequences are widely required in medicine and in biomedical research, but current technologies are non-specific and provide ...
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Hellman Asaf
Dr. Sharon Merims, Hadassah Medical Center Category Life Sciences and Biotechnology    Keywords EGFR inhibitor, skin toxicity, topical Current development stage TRL3 - hypothesis testing and initial POC demonstrated in limited # of ...
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Benny Ofra
Keywords Glioblastoma multiforme, regulatory networks, target genes Current development stage TRL3 - hypothesis testing and initial POC demonstrated in-vitro Application Glioblastoma multiforme (GBM) is a common, very aggressive brain ...
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Hellman Asaf
  Category Life Sciences and Biotechnology    Keywords Cancer, Asthma, Inhibitor, Autotaxin Current development stage  Verified in several preclinical models Our Innovation A new approach to treat metastatic disease has been developed and ...
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Reich Reuven
  Keywords Epigenetics, Dual-specificity, Enzymes, anti-cancer Current Development Stage TRL3 - Hypothesis testing and initial POC demonstrated Application Cancer cells lose their epigenetic checks and balances followed by unscheduled ...
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Ben-Sasson Shmuel
  Category LifeSciences and BioTechnology Keywords Genomics, Cancer Resistance, Species Current development stage General list: TRL3 Experimental proof of concept             Application Mutation in specific genes or variability in ...
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Tabach Yuval
Keywords cell free DNA diagnosis, liquid biopsies, methylation patterns, histone modification Current development stage   TRL3 - hypothesis testing and intial POC demonstrated in limited # of in-vitro modelsApplication The existing sequence ...
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Friedman Nir
  Application No two cancers are the same, and it can be difficult to predict which tumors are slow-growing and which are likely to grow and spread to other parts of the body. Current medical society guidelines rely on cancer stage to determine ...
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Smith Yoav
Category LifeSciences and BioTechnology      Application Primary human hepatocytes are isolated from organs rejected from transplantation. Cells are expensive, show massive batch-to-batch variability and fail to proliferate in culture. ...
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Nahmias Yaakov
  Additional information will be provided upon request
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Mechoulam Raphael
  Additional information will be provided upon request
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Benny Ofra
Category LifeSciences and BioTechnology    Keywords Therapeutic Agents, Liposomes, Biochemistry, Doxorubicin, Sulfate, Alkyl Sulfonate, DoxilTM  Application Current preclinical and clinical data indicate that there is negligible release of ...
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Barenholz Yechezkel
  Additional information will be provided upon request
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Domb Abraham
Category Life Sciences and Bio Technology    Keywords Chemotherapy, Drug resistance * The project is conducted in collaboration with Memorial Sloan-Kettering Cancer Center. Application Cells with multidrug resistance (MDR) due to aberrant ...
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Barenholz Yechezkel
  Category LifeSciences and BioTechnology    Keywords Immunotherapy, CAR-T, BiTe, Biomarker, Immunotherapy repositioning Current development stage TRL4 Technology validated in lab               Our Innovation We found and patented that ...
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Tirosh Boaz
Category Life Sciences and Biotechnology    Keywords Carriers, Cathepsin proteases, Tetra-peptides Current development stage TRL4 - POC & Safety of candidate drug formulation is demonstrated in defined animal model Application The ...
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Blum Galia
  Additional information will be provided upon request
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Mandelboim Ofer
Additional information will be provided upon request
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Golomb Gershon