Protein Secretion is a fundamental aspect in production of therapeutic proteins in eukaryotic cells. Most therapeutic proteins are produced as secreted proteins in mammalian cells such as CHO and HEK293.  An essential milestone in the production ...

Nir-Paz Ran, Hadassah Medical Center Background The World Health Organization has announced antibiotic resistance is one of the biggest threats to global health, food security and development today. Up to 50% of infections in G7 countries may be ...

Background Degenerative diseases become prominent with progressive ageing and thus present the most urgent biomedical challenge facing developed countries to date. One of the most prevalent musculoskeletal diseases caused during aging ...

  Category LifeSciences and BioTechnology    Keywords Pain, Opioid receptor, Addiction, Opioid addiction, Narcotics, AnalgesiaApplication Severe, high-impact chronic pain affects 20 million people in the US annually, and presents a common, ...

  Background Current methods of tissue fixation leave much to be desired, essentially relying on technologies developed from the clothing and carpentry industries i.e. sutures, screws, and pins. Bioadhesives offer a less traumatic method of ...

  Background Neutrophils are potent effector cells in a wide number of infectious, inflammatory and cancerous conditions. Modulation of Neutrophil functions in these conditions may have significant therapeutic benefits and effects on disease ...

Background To date, clinical tests that assess the level of malignancies from patient biopsies rely almost inclusively on histological analysis for specific markers and morphological cues as well as on genetic data i.e mutation analysis. In ...

  Cancer research is moving into the frontiers of how to assign the correct drug(s) to a given patient. Cancer clinicians and researchers commonly search for overexpression of oncogenic biomarkers to assign a targeted treatment, but lack ...

Background   Considerable efforts have been invested in recent years in developing new, effective, yet less toxic drugs for targeted cancer therapy. Currently, this diverse group of drugs includes monoclonal antibodies, immunomodulators, ...

Background The physical size of protein drugs and their susceptibility to degradation are key determinates that make them more dependent on drug delivery technologies. However formulating protein delivery systems so that they maintain their ...

Background Synthetic biology is the discipline of engineering application-driven biological functionalities that were not evolved by nature. Early breakthroughs of cell engineering, which were based on ectopic (over)expression of single sets of ...

Background We have developed a new type of a compact scanning Micro-ellipsometer that operates with a spatial resolution on the sub 10-micron and over a broad spectral range. See Figure (next page). The Micro-ellipsometer can accurately ...

Background Cystic Fibrosis (CF) is an inherited disorder that causes severe damage to the lungs, digestive system and other organs in the body. There is no known cure for cystic fibrosis and the average life expectancy is between 42 and 50 years ...

  https://elsc.huji.ac.il/faculty-staff/yosef-grodzinsky   Background Language disorders affect up to 5% of all children and account for close to 20% of children with disabilities who receive special education. Language disorders make ...

Background The ability to control the shape, size and crystalline state of CaCO3 is significant for several industries including: Powder additives- improved flow properties (spherical shape versus irregular) of ink material, rubber filler, and ...

Our innovation: Neuropathic pain- One of our distinctive results which we optimized recently identifies several compounds that we identified as having a potential protective role in neuropathic pain. We pursued this finding in collaboration with ...

Background Most passion fruit cultivars grown under subtropical climates bear fruit twice a year in the summer and the winter. Peel color is either purple or yellow with the yellow fruit being larger and very sour. Our Innovation We developed ...

Background Obesity is the leading cause of death in America, and is associated with an increase in chronic diseases like, cardiovascular diseases, hypertension, and metabolic disease involving the liver as well as type 2 diabetes. A recent study ...

Background Most passion fruit cultivars grown under subtropical climates bear fruit twice a year, in the summer and the winter. Fruits abscise after ripening. Peel color is either purple or yellow with yellow fruit being larger and very sour. ...

Background Most passion fruit cultivars grown under subtropical climates bear fruit twice a year, in the summer and the winter. Peel color is either purple or yellow with yellow fruit being larger and very sour. Our Innovation We developed an ...