Dr. Eitan Lerner’s lab has diverted its expertise to developing more efficient testing for COVID19. Diagnosis of COVID19 is currently performed via RNA extraction & RT-PCR, which is labor-intensive, time consuming, and requires use of ...

  COVID-19 is a new, highly infectious virus that infects the respiratory system. Severe COVID-19 infection is associated with respiratory failure which may be lethal. One of the major causes for lethal respiratory failure in critically ill ...

Prof. Barenholz is focusing his lab activities on three projects, all aimed at re-purposing drugs with known active ingredients for treatments of viral infection. Project 1: Aims to stop and/or reduce viral penetration and the severe ...

  We propose a spray or mouthwash containing nanoparticles with unique chemical and physical properties that neutralize the virus upon spraying or gargling, by a combination of chemical and irradiation methods.  This proposed mouthwash/spray ...

  We propose an imaging tool that will test the efficacy of a wide range of potential COVID-19 drugs. The imaging tool will enable high-resolution imaging of the infection process of a large number of single cells, by single virus sub-units ...

  There is a growing evidence that the SARS-CoV-2 survives well on various surfaces up to several days (e.g., on plastic and stainless steel). However, it is not clear if the common practice of disinfecting surfaces is optimal, effective or if ...

  Various pathogens (bacteria and viruses as well) bind to specific cell adhesion molecule in order to inhibit the immune response and/or to infect the host cells. However,  upon binding and induction/activation, the cell adhesion molecule ...

  Our Overall Objective is to generate monoclonal antibodies directed against signal peptide (SP) and envelope proteins of COVID-19 for subsequent immune therapy and putative vaccination in the clinical setting. Our Approach is to use ...

  The currently used test for SARS-CoV2 virus uses molecular methods for detecting the presence of viral RNA sequences in subject samples. This is the approved gold standard in the field. The current application of this test requires several ...

  Zinc Based Anti-Viral Spray: Metal ion medication for prevention and treatment of corona virus. Metal ions have been reported to effectively block RNA polymerase in vitro. Thus, increasing the presence of metal ions in the upper part of the ...

We are developing genetically modified plant systems that allow for the identification of SARS-CoV-2 RNA and anti-SARS-CoV-2 antibodies Applications Preventing the spread of the epidemic Restoring economic activity by returning ...

  Edible compounds can be used as potent antiviral agents and, in fact, have been tested successfully against SARS and MERS viruses. They have the potential to be a cure against COVID-19 and are a can be rapidly produced and deployed. These ...

  Recently published research studied the aerosol and surface stability of HCoV-19, the novel human coronavirus that emerged in China in late 2019 and triggered the current pandemic. According to the study’s findings, HCoV-19 remained most ...

  Chip scale photonics technology is developing rapidly for diverse applications, from communication and computation to various types of sensing. The Levy group has pioneered diverse advanced chip scale photonic technologies, including for ...

  Professors Willner and Pikarsky are developing masks and possible ventilation systems that will contain virus neutralizing properties. They have undertaken the development of matrices that neutralize pathogens which can be incorporated into ...

  The goal of this project is to develop environmentally-friendly and non-toxic coating that would prevent the adhesion of viruses. My research group developed a peptide-based coating that prevents adhesion of proteins to surfaces when then ...

  We compare the interaction between the human ACE2 receptor and the SARS-CoV-2 spike protein with that of other pathogenic coronaviruses using molecular dynamics simulations. Molecular dynamics simulations reveal a temporal dimension of ...

Our laboratory has previously generated fusion proteins of a wide range of viral entry receptors. Among these is ACE2, a membrane-bound enzyme which also serves as the entry receptor for the SARS virus. Study of the novel coronavirus discovered ...

Increased blood vessel permeability and vascular leak are a final common pathway in severe influenza and other fatal diseases, such as MERS, Ebola, Coronavirus and sepsis. We have developed at the Hebrew U.- Hadassah Medical School( Prof. ...

Our group has published a lot of work on the SARS Coronavirus. We were the first to characterize an important protein in the virus that has a very unusual structure and sequence (E protein). Moreover, this protein was unique to SARS and was not ...