Obesity is the leading cause of death in America, and is associated with an increase in chronic diseases like, cardiovascular diseases, hypertension, and metabolic disease involving the liver as well as type 2 diabetes. A recent study has shown a correlation between an overexpression of a specific protein and abdominal obesity, however no follow up studies were carried out to indicate a treatment.
The researcher has identified several inhibitory small molecules that specifically target the overexpressed protein responsible for abdominal obesity. A small molecule therapy would inhibit the proteins and reduce or prevent abdominal obesity.
The researcher is looking for sponsored research funding from a partner to:
Identify the best small molecule for inhibiting the overexpressed proteins.
Conduct an in vitro study to elucidate the influence of the small molecule on signaling pathways responsible for abdominal obesity.
Conduct an in vivo study developed in the researcher’s lab to see the influences of the small molecule on the model animal.
Conduct an analysis of the carcass of the model animals.