- Current cancer diagnostic-methods rely on descriptive histopathological data.
- New technology measures patient genomic data against detailed classification of cancer types from databases of measured tumor -genomic expression profiles.
- The method monitors genetic changes enabling better diagnostics and therapeutics.
This new tool measures the similarity between gene data derived from DNA gene tests of a patients malignant tissue with sets of gene test data from pre-classified malignancies (microarray, deep sequencing, Nanostring, etc.). The actual similarity distance obtained provides a powerful and sensitive diagnostic tool for each patient.
Increased diagnostic and detection accuracy, reclassification into new subgroups. A clear similarity value to different clinical states.
Enables cancer diagnosis, prediction of clinical outcomes and formulation of therapeutic approach.
General method may be used for any type of disease if an adequate size sample of microarrays from previously classified disease is available.
Seeking industry cooperation for further development with companies that can prepare datasets
Researcher Information bioinfo.md.huji.ac.il/contact.asp