|Category||Life Sciences and Biotechnology|
|Keywords||Ultra low dose radiation CT scanning, repeat CT scanning|
|Current development stage||For medical device: TRL3 – Hypothesis testing and initial POC is demonstrated in limited number of in-vitro models|
Computer Tomography (CT) studies are pervasive and play a central role in all aspects of patient care, allowing for diagnosis, planning procedures, intra-procedural monitoring, and post-procedural evaluation. The main disadvantage of CT imaging is that it exposes the patient to a substantial amount of ionizing radiation that may be harmful to the patient. This problem is exacerbated for repeat CT scanning, in which a patient is scanned one or more times after a baseline scan has been acquired. Repeat scanning is very common in many clinical situations, e.g. multi-phase scanning, follow-up scanning in oncology, intraoperative monitoring and more. Much research has been recently devoted to developing methods for achieving clinically viable procedures with the lowest possible radiation dose.
We have developed a unique method for dose optimization in repeat CT scanning. The main advantages of the method are:
- It enables a ten-fold radiation dose reduction with very little image quality loss in the ROI.
- It accounts for patient body motions and organs deformations.
- It can be used offline for diagnosis and online for interventional CT.
This technology is expected to provide a competitive edge to manufacturers of CT scanners and to companies developing ultra-low dose X-ray scanning hardware and software. The new method may directly benefit patients who require multiple scans of the same body region and/or are periodically evaluated with CT scan for cancer development.