Lead: Prof. Oded Shoseyov | Department of Plant Sciences, Hebrew University of Jerusalem
Purpose and Vision
- Nanobiomimetics – seeking inspiration in nature’s complex systems
- The research lab explores plant biotechnology and nano-biomaterials
- The lab develops expression of novel recombinant proteins in various expression systems from micro-organisms to plants and their applications as novel nanomaterials
- Advanced nanocomposites for cell culture scaffolds, bioelectronics, tissue engineering, 3D printing, nanosensors
Core Research Expertise
Biotechnology
- Protein engineering and modification including expertise on collagen (human and bovine), cellulose binding proteins, SP1, resilin, humanize antibodies, growth factors, keratin and milk proteins
- Alternative proteins for food science
- RNAi technologies with nanoparticle release mechanisms
- Stem cell differentation on 3D scaffolds for tissue engineering applications including cultured meat, soft human tissues (skin, ligaments, bone)
Biomaterial Innovation
- Fabrication and application of Cellulose Nano Crystals and cellulose based composites
- Scaffold fabrication and characterization: hydrogels, aerogels, directional freezing
- Nanosensors: carbon nanotubes and peptide conjugations for volatile analyte optical sensing on paper based sensors
- Composites for passive radiative cooling and soil regeneration.
Technologies
Biomaterial Production Systems
- Mamallian protein expression in micro-organism and plants
- RNAi delivery for gene expression in plants
- Cellulose nanocrystals from plant, bacterial and tunicate sources
Biotechnology Platforms
- Construct design, transient and stable expression of recombinant proteins in bacteria and plants
- Phenotyipical assays, culture rooms, greehouse and field capabilities
- Multiple plant models, tobacco, arabidopsis, potatoes, eucalyptus and safflower
Innovation Systems
- Self-assembly of natural polymers
- 3D printing, FDM, modular syringe/capillary printing
Application Areas
Sustainable Materials
- Sustainable, degradable and smart packaging solutions
- Biodegradable and flexible advanced electronics composites, for printing, sensing and energy storage application
- Complex hybrid nanocomposites for quantum engineering (plasmonics, CISS effect application)
Biotechnology Applications
- Recombinant protein expression in plants
- Meat and milk proteins
- Tissue engineering for cell differentation on complex scaffolds
