Application

Aquaculture is the fastest growing sector as a source of protein for feeding the expanding world population. Aquaculture also relieveAbstract

Genetically improved carp strains with over 80% survival rate against devastating KHV virus, enabling sustainable and profitable aquaculture production.

Background

The global aquaculture market reached $250 billion in 2022 and is projected to grow at 4.3% CAGR through 2030¹. Common carp represents 4.3 million metric tons of production annually, valued at approximately $8.3 billion². However, Koi Herpesvirus (KHV) outbreaks cause up to 100% mortality in conventional carp stocks, resulting in annual losses exceeding $1 billion³.

Current solutions include:

  • Vaccination available only in Israel and is expensive  with varying effectiveness
  • Biosecurity: low efficacy in outside ponds
  • Traditional breeding: Time-consuming with inconsistent results

Our Innovation

Novel genetic breeding program producing carp strains with inherited resistance to KHV disease, while maintaining commercial growth characteristics.

Key advantages over existing solutions:

  • Over 80% survival rate upon KHV exposure vs. 0-30% in conventional strains
  • Low infectivity reducing disease spread
  • Permanent genetic solution requiring no additional treatments
  • Cost-effective: One-time breeding implementation versus recurring vaccination costs
  • Maintains growth performance of commercial food strains
  • Applicable to various geographical regions and farming conditions

Economic Impact:

  • Reduction in mortality losses during outbreaks without compromising growth
  • Potential to save in prevention costs

Technology

Proprietary breeding program utilizing:

  • Advanced disease challenge models mimicking farm conditions
  • Multi-generational selection process
  • Over 100 families tested for resistance
  • Preservation of desirable commercial traits

The resulting strains demonstrate:

  • High survival rates (>80%) under controlled challenge tests
  • Lower infectivity and disease spread
  • Commercial-grade growth performance
  • Stable inheritance of resistance traits

The current generation of fish look like the original susceptible food strains and have an improved resistance.

Opportunity

We seek industry partners to:

  • Scale up breeding program
  • Validate performance in different geographical regions
  • Establish commercial distribution networks
  • Co-develop region-specific resistant strains

The global carp seed market exceeds $500 million annually⁴, presenting significant commercialization potential for KHV-resistant strains.

Footnotes

Aquaculture Market Insights, Fish Farming International, 2023 (public report)

Allied Market Research, “Aquaculture Market Outlook 2021-2030” (publicly available summary)

FAO Fisheries and Aquaculture Statistics, 2023 (public database)

Global Aquaculture Alliance, “KHV Impact Report 2022” (public summary)